fMRI Cholinergic Mechanisms in Schizophrenia
Status: | Archived |
---|---|
Conditions: | Schizophrenia |
Therapuetic Areas: | Psychiatry / Psychology |
Healthy: | No |
Age Range: | Any |
Updated: | 7/1/2011 |
Start Date: | October 2008 |
End Date: | September 2012 |
This study aims to determine how clozapine treatment improves neuronal measures of sensory
gating in subjects with schizophrenia.
This study will use functional magnetic resonance imaging (fMRI) to study patients treated
with risperidone, a commonly used neuroleptic that does not improves sensory gating, to
those treated with clozapine to determine which brain areas are involved in clozapine's
normalization of sensory gating in schizophrenia.
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