Multiple-Dose Study Apixaban in Pediatric Subjects With an Indwelling Central Venous Catheter
| Status: | Terminated |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 12 - 17 |
| Updated: | 4/8/2017 |
| Start Date: | July 26, 2011 |
| End Date: | July 16, 2012 |
Multiple-Dose Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Apixaban in Pediatric Subjects With an Indwelling Central Venous Catheter
CV185-079 is a multiple dose Apixaban Pharmacokinetics/Pharmacodynamics (PK/PD) study in
pediatric subjects. The objective of this study is primarily to study the PK/PD of Apixaban
in pediatric subjects with a central venous catheter.
pediatric subjects. The objective of this study is primarily to study the PK/PD of Apixaban
in pediatric subjects with a central venous catheter.
Inclusion Criteria:
- Subjects with chronic stable disease with any type of functioning CVC in the upper or
lower venous system (e.g., jugular, subclavian; femoral vein) that is anticipated to
remain in the subject for the treatment portion of the study.
- > 12 to <18 years of age
Exclusion Criteria:
- Current or recent (within 3 months of study drug administration) gastrointestinal
disease or gastrointestinal surgery that, in the opinion of the investigator and the
BMS Medical Monitor, could impact the absorption of the study drug
- Active bleeding or high risk of bleeding
We found this trial at
5
sites
Penn State Hershey Children's Hospital Penn State Milton S. Hershey Medical Center, Penn State College...
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Children's Hospital of Orange County For more than 45 years, CHOC Children’s has been steadfastly...
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Saint Peter's University Hospital Located in New Brunswick, NJ, Saint Peter's University Hospital has been...
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