Brain Computer Interfaces for Functional Recovery From Brain Injury
| Status: | Completed |
|---|---|
| Conditions: | Hospital, Neurology, Epilepsy |
| Therapuetic Areas: | Neurology, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | September 2010 |
| End Date: | August 2013 |
| Contact: | Jeffrey G Ojemann, MD |
| Email: | jojemann@u.washington.edu |
| Phone: | 206-987-4240 |
We will observe epileptic patients who already have electrodes implanted on the brain and
are receiving high-level brain stimulation for clinical purposes while testing their motor
and language function. We propose to do a limited, low-level brain stimulation to show that
the signatures of local activity in the target area change as an effect of brain
stimulation. The goal of this study is to understand the feasibility of a novel recurrent
brain-computer interface that could eventually promote targeted functional recovery in
subjects who have had a brain injury.
are receiving high-level brain stimulation for clinical purposes while testing their motor
and language function. We propose to do a limited, low-level brain stimulation to show that
the signatures of local activity in the target area change as an effect of brain
stimulation. The goal of this study is to understand the feasibility of a novel recurrent
brain-computer interface that could eventually promote targeted functional recovery in
subjects who have had a brain injury.
The subject will have already been scheduled for placement of the ECoG electrodes on the
surface of the brain and who will, for all clinical purposes, subsequently receive
stimulation for mapping of function of the ECoG sites. The decision to place the electrodes
on the brain, the location of the electrodes and the length of time the electrodes are in
are all part of clinical care.
There will be two types of testing, motor and language. Motor will involve inducing
stimulation to the thumb cortex and the wrist cortex. There will be a conditioning of this
over 4-12 hours. Language will involve showing pictures on a computer screen and the subject
will be observed whether speech is disrupted with stimulation or not.
surface of the brain and who will, for all clinical purposes, subsequently receive
stimulation for mapping of function of the ECoG sites. The decision to place the electrodes
on the brain, the location of the electrodes and the length of time the electrodes are in
are all part of clinical care.
There will be two types of testing, motor and language. Motor will involve inducing
stimulation to the thumb cortex and the wrist cortex. There will be a conditioning of this
over 4-12 hours. Language will involve showing pictures on a computer screen and the subject
will be observed whether speech is disrupted with stimulation or not.
Inclusion Criteria:
- Age 18 and older
- Male and Female
- Able to understand English for consenting and testing
- Referred for surgical implantation of electrodes
Exclusion Criteria:
- Under 18 years of age
- Pregnant women
- Prisoners
- Mentally disabled IQ < 70
- Non English Speaking
- Not candidates for surgical implantation of electrodes
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Harborview Medical Center Harborview Medical Center is the only designated Level 1 adult and pediatric...
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