Depression Prevention Initiative - A Study of Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) in School Settings
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Depression |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 12 - 17 |
| Updated: | 4/21/2016 |
| Start Date: | October 2010 |
| End Date: | June 2016 |
Depression Prevention Initiative - A Study of IPT-AST in School Settings
This study is a randomized controlled trial comparing Interpersonal Psychotherapy-Adolescent
Skills Training (IPT-AST) to group counseling (GC) for the prevention of depression in
adolescents. The project will: (1) identify adolescents with elevated depressive symptoms
but who do not meet criteria for a current mood disorder diagnosis; (2) randomize eligible
adolescents to either IPT-AST (N = 100) or GC (N = 100); (3) assess depressive symptoms,
depressive disorders, global functioning, interpersonal functioning, comorbid conditions and
school related indices at baseline, mid-intervention, post-intervention, and at 6-, 12-,
18-, and 24-month follow-up; (4) examine the effects of IPT-AST on depression and various
domains of functioning at each time point; and (5) conduct analyses to examine potential
mediators and moderators of the association between IPT-AST and depression outcomes. This
study will yield data on the efficacy of IPT-AST relative to GC for the prevention of
depressive symptoms and depressive disorders. It will also provide information about the
mechanisms of action of IPT-AST and determine for whom IPT-AST is most effective.
Skills Training (IPT-AST) to group counseling (GC) for the prevention of depression in
adolescents. The project will: (1) identify adolescents with elevated depressive symptoms
but who do not meet criteria for a current mood disorder diagnosis; (2) randomize eligible
adolescents to either IPT-AST (N = 100) or GC (N = 100); (3) assess depressive symptoms,
depressive disorders, global functioning, interpersonal functioning, comorbid conditions and
school related indices at baseline, mid-intervention, post-intervention, and at 6-, 12-,
18-, and 24-month follow-up; (4) examine the effects of IPT-AST on depression and various
domains of functioning at each time point; and (5) conduct analyses to examine potential
mediators and moderators of the association between IPT-AST and depression outcomes. This
study will yield data on the efficacy of IPT-AST relative to GC for the prevention of
depressive symptoms and depressive disorders. It will also provide information about the
mechanisms of action of IPT-AST and determine for whom IPT-AST is most effective.
Inclusion Criteria:
- In 7th-10th grades at intake
- Center for Epidemiologic Studies Depression Scale(CES-D) Score > 16
- At least 2 symptoms on the K-SADS depression section (score of 2 or 3), one of which
is either depressed mood, irritability, or anhedonia
- Adolescent must be English-speaking
- Parent speaks English or Spanish
Exclusion Criteria:
- CES-D Score < 15
- Fewer than 2 depression symptoms on the K-SADS (score of 2 or 3) or 2 or more
symptoms on the K-SADS with no report of depressed mood, irritability, or anhedonia
- Suicide attempt or self-mutilation in the past year, current active suicidal
ideation, and/or history of a clinically significant suicidal behavior (i.e., with
intent to die and high medical lethality) or repeated patterns of self-injurious
behavior
- Presence of current Major Depressive Disorder, dysthymia, substance abuse,
schizophrenia, bipolar disorder, conduct disorder, or psychosis
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