Safety and Efficacy of NNC 0142-0000-0002 in Subjects With Moderately to Severely Active Crohn's Disease



Status:Completed
Conditions:Gastrointestinal, Crohns Disease
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:Any
Updated:11/18/2012
Start Date:February 2011
End Date:January 2014
Contact:Public Access to Clinical Trials - Novo Nordisk
Email:clinicaltrials@novonordisk.com
Phone:Please Contact NN via email

Use our guide to learn which trials are right for you!

A Randomised, Double-blind, Parallel-group, Placebo Controlled Induction Trial to Assess the Clinical Efficacy and Safety of NNC 0142-0000-0002 in Subjects With Moderately to Severely Active Crohn's Disease


This trial is conducted in Europe and North America. The aim of the trial is to assess
disease activity and safety in subjects with moderately to severely active Crohn's disease
(CD) when treated with NNC 0142-0000-0002.


Inclusion Criteria:

- Subjects with CD for at least 3 months

- Subjects not treated before, or subjects who have either not responded to treatment,
or responded and then lost the response during continued administration of a
therapeutic compound

Exclusion Criteria:

- Any of the following: Symptomatic bowel obstruction, short bowel syndrome, ileostomy
or colostomy, surgical bowel resection within 6 months prior to randomisation or
clinically relevant un-drained abscess

- History of dysplasia or malignancy in the colon

- Any ongoing chronic or active infectious disease or microbial infection requiring
systemic oral or intravenous treatment against infection within 1 month prior to
randomisation

- Body mass index (BMI) higher or equal to 38.0 kg/m^2
We found this trial at
8
sites
Milwaukee, Wisconsin 53209
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
Arlington, Virginia 22201
?
mi
from
Arlington, VA
Click here to add this to my saved trials
Chicago, Illinois 60607
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Detroit, Michigan 48201
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Erlanger, Kentucky 41018
?
mi
from
Erlanger, KY
Click here to add this to my saved trials
Hyattsville, Maryland 20782
?
mi
from
Hyattsville, MD
Click here to add this to my saved trials
Memphis, Tennessee 38163
?
mi
from
Memphis, TN
Click here to add this to my saved trials
Morehead City, North Carolina 28557
?
mi
from
Morehead City, NC
Click here to add this to my saved trials