A Comparison of Cognitive and Dynamic Therapy for Depression in Community Settings
| Status: | Completed |
|---|---|
| Conditions: | Depression, Major Depression Disorder (MDD) |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 7/11/2015 |
| Start Date: | November 2010 |
| End Date: | July 2014 |
| Contact: | Jacqueline K Lee, B.A. |
| Email: | jacquel@mail.med.upenn.edu |
| Phone: | 215-349-5222 |
A Comparison of Cognitive and Dynamic Therapy for MDD in Community Settings
The goal of this study is to compare supportive-expressive therapy, a type of psychodynamic
psychotherapy, with cognitive therapy for the treatment of depression in community mental
health consumers.
Hypothesized mediators of treatment will also be examined.
psychotherapy, with cognitive therapy for the treatment of depression in community mental
health consumers.
Hypothesized mediators of treatment will also be examined.
The goal of this study is to conduct a randomized, comparative, non-inferiority clinical
trial that tests the hypothesis that a widely used form of manualized dynamic psychotherapy
(supportive-expressive psychodynamic therapy) is not inferior to cognitive therapy when
implemented in community mental health settings for the treatment of major depressive
disorder (MDD). The specific aims are (1) to conduct a randomized non-inferiority trial to
compare supportive-expressive psychodynamic therapy and cognitive therapy for patients with
MDD and (2) to assess the comparative effectiveness of supportive-expressive psychodynamic
therapy and cognitive therapy on secondary measures of symptoms, patient functioning, and
quality of life.
Patient mediators of outcome will also be examined through an additional grant awarded to
Paul Crits-Christoph, Ph.D. This grant was funded by the National Institutes of Mental
Health - RO1MH092363-01. This grant is entitled:"The mechanisms of cognitive and dynamic
therapy in community settings."
Recruitment will occur solely through community mental health clinics in and around
Philadelphia.
trial that tests the hypothesis that a widely used form of manualized dynamic psychotherapy
(supportive-expressive psychodynamic therapy) is not inferior to cognitive therapy when
implemented in community mental health settings for the treatment of major depressive
disorder (MDD). The specific aims are (1) to conduct a randomized non-inferiority trial to
compare supportive-expressive psychodynamic therapy and cognitive therapy for patients with
MDD and (2) to assess the comparative effectiveness of supportive-expressive psychodynamic
therapy and cognitive therapy on secondary measures of symptoms, patient functioning, and
quality of life.
Patient mediators of outcome will also be examined through an additional grant awarded to
Paul Crits-Christoph, Ph.D. This grant was funded by the National Institutes of Mental
Health - RO1MH092363-01. This grant is entitled:"The mechanisms of cognitive and dynamic
therapy in community settings."
Recruitment will occur solely through community mental health clinics in and around
Philadelphia.
Inclusion Criteria:
- Confirmed diagnosis of major depressive disorder
- Able to read at the 4th grade level or higher
- Willingness to be randomized and participate in research
Exclusion Criteria:
- Current or past diagnosis of schizophrenia, seizure disorder, bipolar disorder,
psychotic features, or clinically significant organic pathology
- Significant suicidal risk/ideation requiring immediate referral for more intensive
treatment, or specific gesture in the last 6 months
- Current substance abuse or dependence requiring immediate referral to substance abuse
program
- Acute medical problem requiring immediate inpatient treatment
- Need for referral to a partial hospitalization program
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