A Study of Radiation Toxicity in the Liver Using MRI-Based Perfusion
| Status: | Recruiting |
|---|---|
| Conditions: | Liver Cancer, Cancer, Cancer, Other Indications |
| Therapuetic Areas: | Oncology, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/7/2018 |
| Start Date: | November 2006 |
| End Date: | October 2019 |
| Contact: | Cancer Answer Line |
| Email: | canceranswerline@umich.edu |
| Phone: | 1-800-865-1125 |
A Pilot Study of Radiation Toxicity in the Liver Using MRI-Based Perfusion
Researchers at the the University of Michigan are conducting a research project to assess how
a course of radiation therapy changes the way blood flows through the liver. To be able to do
this, the researchers will be using MRI (magnetic resonance imaging) scans completed before,
during, and after radiation therapy. MRI's will be done on 4 or 5 occasions. On each
occasion, you will be injected with a fluid called gadolinium (a contrast agent) before
getting an MRI. This contrast agent makes it easier for the Researchers to see your organs in
the scans, and causes any abnormal areas to become very bright on the MRI. This agent will be
injected into a vein in your arm or leg. Each MRI scan will last approximately 45 minutes.
a course of radiation therapy changes the way blood flows through the liver. To be able to do
this, the researchers will be using MRI (magnetic resonance imaging) scans completed before,
during, and after radiation therapy. MRI's will be done on 4 or 5 occasions. On each
occasion, you will be injected with a fluid called gadolinium (a contrast agent) before
getting an MRI. This contrast agent makes it easier for the Researchers to see your organs in
the scans, and causes any abnormal areas to become very bright on the MRI. This agent will be
injected into a vein in your arm or leg. Each MRI scan will last approximately 45 minutes.
Inclusion Criteria:
- Patients must be ≥18 years of age.
- The patient's planned cancer management is radiation to the liver with or without
chemotherapy.
- Patients must have a performance status of 0-2 and a life expectancy of at least 3
months.
- Patients should have no contraindications to having a contrast enhanced MRI scan.
Exclusion Criteria:
- Women who are pregnant or breastfeeding are excluded.
- Prisoners are excluded
We found this trial at
1
site
1500 East Medical Center Drive
Ann Arbor, Michigan 48109
Ann Arbor, Michigan 48109
Phone: 734-647-9956
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