Measure of Cerebrospinal Fluid (CSF) Pressure Variation With Patient Positioning

Volunteers who need a myelogram of their spine as part of their routine medical care are
being asked to be in this study. A myelogram is an imaging study with x-rays after an agent
is put into the spine that shows spinal fluid on the x-ray. It requires insertion of a
needle into the cerebrospinal fluid (CSF) inside the spine. CSF is a bodily fluid that
bathes the brain, spinal cord, and nerve roots. This study is being conducted to measure
CSF pressure changes with different patient positioning.

We are motivated to do this research study to better treat patients who develop a spinal
fluid leak during a myelogram or other spine procedure. The tissue that holds the
cerebrospinal fluid (CSF) is called the dura. During surgery or other procedures, the dura
can develop a tear. Dural tears can result in a leakage of CSF. CSF leaks are a recognized
complication of spinal surgery. Currently, there is no evidence on whether or not a
specific postoperative spine position is beneficial, especially for cervical (neck spine)
CSF leaks. The process of dural healing after a dural tear is influenced by CSF pressure.
High CSF pressure may inhibit dural healing. We want to find the patient position (sitting,
lying down, or reclining) that reduces the CSF pressure the most. To do this, we want to
attach a pressure monitor to the needle that is normally placed in the spine for a myelogram
and measure the CSF pressure.

Inclusion Criteria:

- Need a lumbar or cervical myelogram as part of routine care.

Exclusion Criteria:

- Not needing a myelogram in the cervical or lumbar spine.