Study of Gene Associations and Infertility
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Women's Studies, Infertility |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 4/6/2019 |
| Start Date: | February 2006 |
| End Date: | December 2025 |
Genes and Gene Polymorphisms Associated With Infertility: Utilization of DNA Characteristics to Better Understand Reproductive Competence
The purpose of this this study is to use DNA screening strategies to identify genes and
localize genomic regions that are differentially expressed in patients with infertility to
further understand the genetic basis for reproductive competence.
localize genomic regions that are differentially expressed in patients with infertility to
further understand the genetic basis for reproductive competence.
Experimental strategies seek to discover small variants in DNA sequences, which are
associated with certain infertility parameters. The alleles being analyzed in in vitro
fertilization (IVF) population are sought to be associated with functional differences in the
expression of the gene product that are then mechanistically linked to infertility.
associated with certain infertility parameters. The alleles being analyzed in in vitro
fertilization (IVF) population are sought to be associated with functional differences in the
expression of the gene product that are then mechanistically linked to infertility.
Inclusion Criteria:
- all patients undergoing fertility care
Exclusion Criteria:
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