Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Patients With Hormone Receptor-Positive Breast Cancer and Resistance to Non-Steroidal Aromatase Inhibitors
| Status: | Completed |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/24/2017 |
| Start Date: | December 2010 |
| End Date: | November 2014 |
A Phase 2 Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Hormone Receptor-Positive Breast Cancer Subjects With Acquired Resistance to Non-Steroidal Aromatase Inhibitors
The purpose of this study is to evaluate oral doses of BMS-754807 in combination with
letrozole or BMS-754807 alone are safe and efficacious in locally advanced or metastatic
hormone receptor positive breast cancer subjects who have progressed with prior
non-steroidal aromatase inhibitor treatment.
letrozole or BMS-754807 alone are safe and efficacious in locally advanced or metastatic
hormone receptor positive breast cancer subjects who have progressed with prior
non-steroidal aromatase inhibitor treatment.
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com.
Inclusion Criteria:
- Postmenopausal women with hormone receptor-positive and HER-2 negative breast cancer
- Disease progression following non-steroidal aromatase inhibitor treatment
Exclusion Criteria:
- Known symptomatic brain metastasis
- Medical condition requiring chronic steroids
- History of Type 1 or 2 Diabetes
- Uncontrolled or significant cardiovascular (CV) disease
- Concomitant second malignancies
We found this trial at
17
sites
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins The name Johns Hopkins has become synonymous...
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Mayo Clinic Mayo Clinic's campus in Arizona provides medical care for thousands of people from...
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425 E River Pkwy # 754
Minneapolis, Minnesota 55455
Minneapolis, Minnesota 55455
612-624-2620
Masonic Cancer Center at University of Minnesota The Masonic Cancer Center was founded in 1991....
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University of Virginia Health System UVA Health System includes a 604-bed hospital, level I trauma...
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University of Chicago Medical Center The University of Chicago Medicine has been at the forefront...
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University of Wisconsin In achievement and prestige, the University of Wisconsin–Madison has long been recognized...
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Mayo Clinic Arizona Mayo Clinic in Arizona provides medical care for thousands of people from...
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