Ceftriaxone in Non-neutropenic Fever
Status: | Completed |
---|---|
Conditions: | Cancer, Cancer, Infectious Disease |
Therapuetic Areas: | Immunology / Infectious Diseases, Oncology |
Healthy: | No |
Age Range: | Any - 22 |
Updated: | 5/27/2013 |
Start Date: | August 2010 |
End Date: | December 2010 |
Contact: | adam esbenshade, M.D., M.S.C.I |
Email: | adam.esbenshade@vanderbilt.edu |
Phone: | 615-936-1762 |
This is a retrospective chart review of all patients cared for at Monroe Carell Jr.
Children's Hospital at Vanderbilt including the following:
- patients between 2007-2009 with malignancy, Langerhans cell histiocytosis (LCH) or
hemophagocytic lymphohistiocytosis (HLH) and a central venous catheter who were under
23 years of age at time of diagnosis in order to ascertain the associated symptoms,
management and outcome of all episodes of non-neutropenic fever.
- to identify a subset of low-risk patients that can be safely managed without use of
empiric antibiotics.
Inclusion Criteria:
- Diagnosed with malignancy, Langerhans cell histiocytosis,or hemophagocytic
lymphohistiocytosis from 2007 through 2009
- Under 23 years at time of diagnosis of malignancy, Langerhans cell histiocytosis,or
hemophagocytic lymphohistiocytosis
- Treated at Monroe Carell Jr. Children's Hospital at Vanderbilt for aforementioned
diagnosis from 2007 through 2010
- While on immunosuppressive therapy with a central venous line in place had at least
one documented episode of fever (defined as ≥ 38.0°Celsius orally for over 30 minutes
or ≥ 38.3°Celsius orally x1).
Exclusion Criteria:
- Does not meet all inclusion criteria as stated above
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