Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated Influenza

This is a randomized clinical trial designed to evaluate the safety/efficacy of two dosing
regimens of oral nitazoxanide compared to placebo in the treatment of acute uncomplicated
influenza in adults and adolescents. The investigators hypothesize that treatment with
Nitazoxanide will reduce the duration of symptoms in patients with confirmed influenza
infection. Secondarily, the investigators hypothesize that treatment with nitazoxanide will
reduce the complications of influenza, severity of symptoms, time lost from work, time to
return to normal daily activities.