Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer

PRIMARY OBJECTIVES:

I. To conduct a randomized trial of a culturally-informed pre-genetic cancer risk assessment
(GCRA) telephone intervention.

II. To evaluate the effect of the pre-GCRA intervention versus a time and attention control
versus standard scheduling procedure alone (usual care) on levels of anxiety, perceived
personal control and cancer genetics knowledge.

III. To explore patients' experiences with the pre-GCRA intervention through
post-intervention telephone interviews.

SECONDARY OBJECTIVES:

I. To explore patients' perceived barriers to GCRA through no-show telephone interviews.

OUTLINE:

Patients are randomized to 1 of 3 treatment arms.

ARM I: Patients receive a culturally-informed adapted motivational interviewing telephone
call.

ARM II: Patients participate in a controlled condition comprising a health habits
intervention group.

ARM III: Patients receive usual care comprising a standard scheduling phone call and proceed
with normal GCRA process. All patients are mailed standard new patient packets containing
questionnaires on demographics and personal health history, and a family history form. All
patients then undergo genetic cancer risk assessment.

Inclusion Criteria:

- Individuals who have a personal history of hereditary breast or ovarian cancer; a
subset of 60 women without a personal history of hereditary or ovarian cancer will be
included in an exploratory subset analysis

- Meet NCCN criteria for consideration of genetic testing for hereditary breast cancer

- Willing to sign consent

- Pregnant women and women of child-bearing potential are eligible for participation in
this study

- Women who report themselves to be of Latino or Hispanic ethnic background (defined as
Spanish, Mexican, Central or South American, Cuban, Puerto Rican, Dominican, or other
Hispanic origin)

- Women who are under- or uninsured and come from low-income communities

- Ability to understand English or Spanish

Exclusion Criteria:

- Previous participation in GCRA