A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy



Status:Terminated
Conditions:Lymphoma, Psychiatric
Therapuetic Areas:Oncology, Psychiatry / Psychology
Healthy:No
Age Range:18 - Any
Updated:1/10/2019
Start Date:April 4, 2011
End Date:March 28, 2014

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

AN OPEN-LABEL, RANDOMIZED, PHASE 3 STUDY OF INOTUZUMAB OZOGAMICIN ADMINISTERED IN COMBINATION WITH RITUXIMAB COMPARED TO DEFINED INVESTIGATOR'S CHOICE THERAPY IN SUBJECTS WITH RELAPSED OR REFRACTORY CD22-POSITIVE AGGRESSIVE NON-HODGKIN LYMPHOMA WHO ARE NOT CANDIDATES FOR INTENSIVE HIGH-DOSE CHEMOTHERAPY

The purpose of this study is to evaluate the efficacy of inotuzumab ozogamicin plus rituximab
in relapsed/refractory aggressive Non-Hodgkin lymphoma patients who are not candidates for
intensive high-dose chemotherapy. Specifically, the goal is to demonstrate the superiority of
this combination compared with an active comparator arm (investigator's choice of
rituximab+bendamustine or rituximab+gemcitabine) using the primary endpoint of overall
survival.


Inclusion Criteria:

Exclusion Criteria:
We found this trial at
78
sites
Stony Brook University Medical Center
101 Nicolls Rd
Stony Brook, New York 11794
(631) 444-4000
Stony Brook University Medical Center Stony Brook Medicine expresses our shared mission of research, clinical...
?
mi
from
Stony Brook, NY
Click here to add this to my saved trials
Baylor University Medical Center
3500 Gaston Avenue
Dallas, Texas 75246
1.800.422.9567
Baylor University Medical Center Baylor University Medical Center in Dallas, TX is ranked nationally in...
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Barbara Ann Karmanos Cancer Institute
4100 John R
Detroit, Michigan 48201
800-527-6266
Barbara Ann Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Shands Hospital at the University of Florida
Gainesville, Florida 32610
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Baptist Medical Center
Jacksonville, Florida 32207
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Advanced Medical Specialties
8940 N Kendall Dr # 300E
Miami, Florida 33176
?
mi
from
Miami, FL
Click here to add this to my saved trials
Beth Israel Med Ctr
305 1st Avenue # Dazian 7
New York, New York 10003
(212) 420-2806
Beth Israel Med Ctr The physicians and staff of Mount Sinai Beth Israel's Heart Institute...
?
mi
from
New York, NY
Click here to add this to my saved trials
St Luke's - Roosevelt Hospital Center
1111 Amsterdam Ave
New York, New York 10025
(212) 523-4000
St Luke's - Roosevelt Hospital Center With 523 beds, Mount Sinai St. Luke's serves as...
?
mi
from
New York, NY
Click here to add this to my saved trials
Georgia Regents Medical Cancer Pharmacy
Augusta, Georgia 30912
?
mi
from
Augusta, GA
Click here to add this to my saved trials
Augusta University
1120 15th Street
Augusta, Georgia 30912
(706) 721-0211
Georgia Regents University Georgia Regents University, home of the Medical College of Georgia, is one...
?
mi
from
Augusta, GA
Click here to add this to my saved trials
Mount Sinai Comprehensive Cancer Center, Aventura
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
University Cancer Institute, LLC
Boynton Beach, Florida 33426
?
mi
from
Boynton Beach, FL
Click here to add this to my saved trials
Disney Family Cancer Center at Providence St Joseph Medical Center
Burbank, California 91505
?
mi
from
Burbank, CA
Click here to add this to my saved trials
Providence St. Joseph Medical Center
Burbank, California 91505
?
mi
from
Burbank, CA
Click here to add this to my saved trials
The University Hospital
Cincinnati, Ohio 45219
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Kootenai Cancer Center
Coeur d'Alene, Idaho 83814
?
mi
from
Coeur d'Alene, ID
Click here to add this to my saved trials
Good Samaritan Hospital, Corvallis
Corvallis, Oregon 97330
?
mi
from
Corvallis, OR
Click here to add this to my saved trials
Samaritan Ambulatory Infusion Services
Corvallis, Oregon 97330
?
mi
from
Corvallis, OR
Click here to add this to my saved trials
University Hospital - St. Paul
Dallas, Texas 75235
?
mi
from
Dallas, TX
Click here to add this to my saved trials
University Hospital - Zale Lipshy
Dallas, Texas 75235
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Baylor Charles A Sammons Cancer Center
Dallas, Texas 75246
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Simmons Comprehensive Cancer Center
Dallas, Texas 75390
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Decatur Memorial Hospital (DMH)
Decatur, Illinois 62526
?
mi
from
Decatur, IL
Click here to add this to my saved trials
Barbara Ann Karmanos Cancer Institute at farmington Hills
Farmington Hills, Michigan 48334
?
mi
from
Farmington Hills, MI
Click here to add this to my saved trials
21st Century Oncology of Jacksonville, LLC
Fernandina Beach, Florida 32034
?
mi
from
Fernandina Beach, FL
Click here to add this to my saved trials
Hematology-Oncology Medical Group of Fresno Inc
Fresno, California 93720
?
mi
from
Fresno, CA
Click here to add this to my saved trials
Davis Cancer Pavilion and Shands Medical Plaza
Gainesville, Florida 32608
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Shands Cancer Hospital at the University of Florida
Gainesville, Florida 32608
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
UF Health Davis Cancer Pavillion and Shands Med Plaza
Gainesville, Florida 32608
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
UF Health Shands Cancer Hospital
Gainesville, Florida 32608
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
UF Health Shands Hospital
Gainesville, Florida 32610
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Penn State Milton S. Hershey Medical Center
500 University Dr
Hershey, Pennsylvania 17033
(717) 531-6955
Penn State Milton S. Hershey Medical Center Penn State Milton S. Hershey Medical Center, Penn...
?
mi
from
Hershey, PA
Click here to add this to my saved trials
University of Texas M.D. Anderson Cancer Center
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
?
mi
from
Houston, TX
Click here to add this to my saved trials
21st Century Oncology of Jacksonville, Inc.
Jacksonville, Florida 32034
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Baptist Cancer Institute
Jacksonville, Florida
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
University of Kansas Medical Center
3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
Thompson Oncology Group
1915 White Avenue
Knoxville, Tennessee 37916
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
Medical Specialists Of Palm Beaches
Lake Worth, Florida 33467
?
mi
from
Lake Worth, FL
Click here to add this to my saved trials
Universitaire Ziekenhuizen Leuven
Leuven, Vlaams Brabant
?
mi
from
Leuven,
Click here to add this to my saved trials
University of Kentucky A.B. Chandler Medical Center
Lexington, Kentucky 40536
?
mi
from
Lexington, KY
Click here to add this to my saved trials
University of Kentucky, Markey Cancer Center
Lexington, Kentucky
?
mi
from
Lexington, KY
Click here to add this to my saved trials
Southeast Nebraska Hematology & Oncology Consultants, P.C. d/b/a Southeast Nebraska Cancer Center
Lincoln, Nebraska 68510
?
mi
from
Lincoln, NE
Click here to add this to my saved trials
Ronald Reagan UCLA Medical Center, Drug Information Center, Department of Pharmaceutical Services
Los Angeles, California 90095
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Clinical Research Unit
Los Angeles, California 90024
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Peter Morton Medical Plaza
Los Angeles, California 90095
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Ronald Reagan UCLA Medical Center
Los Angeles, California 90095
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Thompson Oncology Group
Maryville, Tennessee 37804
?
mi
from
Maryville, TN
Click here to add this to my saved trials
Mercy Hospital
Miami, Florida 33133
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mercy Research Institute
Miami, Florida
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mount Sinai Comprehensive Cancer Center
Miami Beach, Florida 33140
?
mi
from
Miami Beach, FL
Click here to add this to my saved trials
Mount Sinai Medical Center
Miami Beach, Florida 33140
?
mi
from
Miami Beach, FL
Click here to add this to my saved trials
Floyd Memorial Cancer Center of Indiana
New Albany, Indiana 47150
?
mi
from
New Albany, IN
Click here to add this to my saved trials
Tulane University Hospital & Clinic
New Orleans, Louisiana 70112
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
Beth Israel Comprehensive Cancer Center
New York, New York
?
mi
from
New York, NY
Click here to add this to my saved trials
Memorial Sloan Kettering Cancer Center
1275 York Ave
New York, New York 10021
(212) 639-2000
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
?
mi
from
New York, NY
Click here to add this to my saved trials
Samaritan Pacific Coast Hospital
Newport, Oregon 97365
?
mi
from
Newport, OR
Click here to add this to my saved trials
OU Medical Center Presbyterian Professional Building
Oklahoma City, Oklahoma 73104
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
OU Medical Center Presbyterian Tower
Oklahoma City, Oklahoma 73104
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Peggy and Charles Stephenson Cancer Center (chemo & infusion)
Oklahoma City, Oklahoma 73104
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Peggy and Charles Stephenson Cancer Center (clinic location)
Oklahoma City, Oklahoma 73104
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
21st Century Oncology of Jacksonville, LLC
Orange Park, Florida 32073
?
mi
from
Orange Park, FL
Click here to add this to my saved trials
Kootenai Cancer Center
Post Falls, Idaho 83854
?
mi
from
Post Falls, ID
Click here to add this to my saved trials
Barnes Jewish Hospital
Saint Louis, Missouri 63110
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Washington University in St. Louis
Saint Louis, Missouri 63110
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Washington University
Saint Louis, Missouri 63110
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Washington University School of Medicine
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Park Nicollet Frauenshuh Cancer Center
Saint Louis Park, Minnesota 55426
?
mi
from
Saint Louis Park, MN
Click here to add this to my saved trials
Barnes-Jewish St. Peters
Saint Peters, Missouri 63376
?
mi
from
Saint Peters, MO
Click here to add this to my saved trials
Sansum Clinic
Santa Barbara, California 93105
?
mi
from
Santa Barbara, CA
Click here to add this to my saved trials
UCLA Santa Monica Hematology-Oncology
Santa Monica, California 90404
?
mi
from
Santa Monica, CA
Click here to add this to my saved trials
Guthrie Clinic, Ltd.
Sayre, Pennsylvania 18840
?
mi
from
Sayre, PA
Click here to add this to my saved trials
Robert Packer Hospital
Sayre, Pennsylvania 18840
?
mi
from
Sayre, PA
Click here to add this to my saved trials
Thompson Oncology Group
Sevierville, Tennessee 37862
?
mi
from
Sevierville, TN
Click here to add this to my saved trials
Sansum Clinic
Solvang, California 93463
?
mi
from
Solvang, CA
Click here to add this to my saved trials
Stony Brook University Medical Center Cancer Center
Stony Brook, New York 11794
?
mi
from
Stony Brook, NY
Click here to add this to my saved trials
Howard University Hospital
Washington, District of Columbia 20060
?
mi
from
Washington,
Click here to add this to my saved trials
West Chester Hospital Medical Building
West Chester, Ohio 45069
?
mi
from
West Chester, OH
Click here to add this to my saved trials
University of Kansas Cancer Center and Medical Pavilion
Westwood, Kansas 66205
?
mi
from
Westwood, KS
Click here to add this to my saved trials