Computer-Guided Glucose Management Systems in Treating Patients With Hyperglycemia Who Have Undergone Blood and Bone Marrow Transplant



Status:Recruiting
Conditions:Cancer, Brain Cancer, Blood Cancer, Infectious Disease, Lymphoma, Women's Studies, Hematology, Diabetes
Therapuetic Areas:Endocrinology, Hematology, Immunology / Infectious Diseases, Oncology, Reproductive
Healthy:No
Age Range:18 - Any
Updated:4/13/2015
Start Date:December 2012

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Use of a Computer-Guided Glucose Management System for Patients Undergoing Blood and Marrow Transplants (BMT)

This clinical trial studies computer-guided glucose management systems in treating patients
with hyperglycemia who have undergone blood and bone marrow transplant. A computer-guided
glucose management system may help manage glucose levels in patients who have undergone
blood or bone marrow transplant.

PRIMARY OBJECTIVES:

I. To examine the ability of computer-guided glucose management system (CGGMS) algorithms to
control glucose within or close to current University of Washington Medical Center (UWMC)
intensive care unit (ICU) targets (100 to 140 mg/dl) in non-critically ill bone marrow
transplant (BMT) adult (age >= 18 years) patients.

OUTLINE:

Patients receive blood glucose management with intravenous (IV) insulin using Glucommander.

Inclusion Criteria:

- Post-transplant adult patients (age >= 18 years) on the BMT Service at UWMC

- Requiring insulin secondary to:

- Known history of (h/o) type 2 diabetes mellitus

- Two blood sugar values > 180 (point of care and/or am lab glycemia)

- One blood sugar value > 250 (point of care or AM lab glycemia)

Exclusion Criteria:

- Critically ill patients (intensive care unit [ICU] admissions)

- Terminally ill patients

- Eastern Cooperative Oncology Group (ECOG) performance status > 3

- Previous type 1 diabetes mellitus

- Cognitively impaired patients, unable to consent
We found this trial at
2
sites
55 Fruit St
Boston, Massachusetts 02114
(617) 724-4000
Massachusetts General Hospital Cancer Center An integral part of one of the world
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1100 Fairview Avenue North
Seattle, Washington 98109
206-667-4584
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium The Fred Hutchinson/University of Washington Cancer...
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Seattle, WA
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