Post-Operative Sub-Tenon Kenalog in Glaucoma Filtering Surgery

Postoperative sub-Tenon Triamcinolone Acetonide in glaucoma filtering surgery

Objectives: Trabeculectomy is a surgical procedure designed to reduce internal eye pressure
by draining fluid from within the eye to the sub-conjunctival (superficial eye lining)
space. Scar formation from conjunctival and Tenon's capsule fibroblast proliferation
represents the most common cause of failure of trabeculectomies. A number of drugs have been
use to prevent failure of trabeculectomies from the scarring process including
intraoperative mitomycin C (MMC) and preoperative Triamcinalone Acetonide (TA). Over the
past several years, intraoperative MMC has become a preferred method of preventing scar
formation. This study looks to determine in a prospective, double-blind, randomized method
the long-term efficacy and safety of MMC with postoperative TA compared to the standard
practice of intraoperative MMC with postoperative prednisolone acetate drops in preventing
scar related failures of trabeculectomies.

Inclusion Criteria:Trabeculectomy surgery patient, age 18 or older - Exclusion
Criteria:Pregnant, nursing, age less than 18, known allergy to medication being studied