Assessment of Combined Bowel Preparation for Capsule Endoscopy Study



Status:Completed
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:April 2010
End Date:November 2013

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Trial Summary
Trial Overview
Inclusion Criteria
The investigators are conducting a study to see if taking a bowel preparation before having
a capsule endoscopy is more helpful than the standard preparation of not eating after 7 PM
the night before a capsule endoscopy in making it easier to see the small bowel in order to
find the source of gastrointestinal bleeding.

This is a single-blind, prospective randomized controlled study to determine if a
combination of purgative agent, prokinetic agent, simethicone, and position will improve
small bowel visualization, diagnostic yield, and completion rate of capsule endoscopy.

Inclusion Criteria:

1. Age > 18 years old

2. Gastrointestinal bleeding as indication for capsule endoscopy.

3. Ability to give informed consent

Exclusion Criteria:

1. Subject has an allergy to polyethylene glycol or other adverse reaction to a previous
bowel preparation with PEG3350 (MoviPrep®), metoclopramide, or simethicone;

2. Subjects has gastrointestinal motility disorder;

3. Subjects had stomach or small bowel resection;

4. Pregnancy;

5. Subjects has pheochromocytoma;

6. Subjects has uncontrolled hypertension;

7. Subjects has seizure disorders;

8. Subjects has concurrent MAO inhibitor use;

9. Subject has G6PD deficiency;

10. Subjects has swallowing disorder (including impaired gag reflex);

11. Subjects has hyponatremia with serum sodium less than 130 mm0l/L
We found this trial at
1
site
The Mayo Clinic
Rochester, Minnesota 55905
?
mi
from
Rochester, MN
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