Mouse Allergen and Asthma Intervention Trial



Status:Completed
Conditions:Allergy, Asthma
Therapuetic Areas:Otolaryngology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:6 - 17
Updated:3/17/2017
Start Date:November 2010
End Date:September 2016

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Trial Summary
Trial Overview
Inclusion Criteria
The MAAIT is a randomized, controlled trial of a home intervention to reduce mouse allergen
exposure in mouse allergic children with asthma and mouse allergen exposure. Participants
will be randomized to either the Integrated Pest Management (IPM) Group or the Education
Group. The IPM Group will receive professional mouse abatement, education, two HEPA filters,
allergen-proof mattress and pillow encasements, and targeted cleaning. The Education Group
will receive education about IPM at the beginning of the trial and then after completion of
the trial, will receive the IPM intervention. Participants will be followed for 12 months.


Inclusion Criteria:

- persistent asthma

- exacerbation, previous 12 months

- evidence of mouse sensitization

- high levels of mouse allergen in home

- ages 5-17 years

Exclusion Criteria:

- intermittent asthma

- no exacerbation in previous 12 months

- not sensitized to mouse

- low or undetectable mouse allergen in home

- other lung disease aside from asthma
We found this trial at
2
sites
Johns Hopkins
Baltimore, Maryland 21218
(410) 516-8000
Johns Hopkins The Johns Hopkins University opened in 1876, with the inauguration of its first...
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Boston Children's
Boston, Massachusetts 02210
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Boston, MA
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