Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern
| Status: | Completed |
|---|---|
| Conditions: | Angina, Peripheral Vascular Disease, Peripheral Vascular Disease, Cardiology, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 21 - 99 |
| Updated: | 2/2/2019 |
| Start Date: | November 2010 |
| End Date: | June 2012 |
Investigation of a Molecular Personalized Coronary Gene Expression Test on Cardiology Practice Pattern
To investigate whether the use of Corus CAD (Age/Sex/Gene Expression score - ASGES) blood
assay changes the diagnostic testing pattern in patients referred to a cardiologist for the
evaluation of chest pain or anginal equivalent symptoms.
assay changes the diagnostic testing pattern in patients referred to a cardiologist for the
evaluation of chest pain or anginal equivalent symptoms.
A prospective cohort of 88 subjects receiving the Corus CAD (Age/Sex/Gene Expression score -
ASGES) assay were compared to a retrospective cohort of 83 subjects that did not receive the
assay.
ASGES) assay were compared to a retrospective cohort of 83 subjects that did not receive the
assay.
Inclusion Criteria:
1. Stable chest pain, typical or atypical angina or anginal equivalent
2. The patient has signed the appropriate Institutional Review Board approved Informed
Consent Form.
Exclusion Criteria:
1. History of myocardial infarction
2. Current myocardial infarct (MI) or acute coronary syndrome
3. Current New York Heart Association (NYHA) class III or IV congestive heart failure
symptoms
4. Any previous coronary revascularization
5. Any individuals with:
1. Diabetes
2. Suspected unstable angina
3. Systemic infections
4. Systemic inflammatory conditions
6. Any individuals currently taking:
1. Steroids
2. Immunosuppressive agents
3. Chemotherapeutic agents
7. Recipient of any organ transplant
We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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