Adherence, Improvement Measure (AIM) System

In this project, we will work directly with underserved patients in a safety-net setting to
conduct a randomized clinical trial of standard-of-care adherence counseling versus a novel
adherence intervention embedded in an existing PHR that uses cellular phone short message
service (SMS) reminders and patient responses to the reminders. We will compare adherence
rates in both arms as assessed by antiretroviral medication concentrations in hair samples
and self-report; clinical outcomes will also be compared in the two arms. The project will
examine medication adherence for antiretroviral medications and treatments of common
conditions such as depression, hypertension, diabetes and hypercholesterolemia.