Acute Cough Study In Children

In light of protocol changes required due to methodological and operational issues, including
background noise in cough recordings which could impact data interpretation, the study has
been terminated.

Inclusion Criteria:

Male or female healthy children ages 6 to under 12 years who are symptomatic with a cough
due to a cold or acute URTI characterized by:

- Onset of cold/URTI symptoms occurring no more than 10 days prior to Visit 1;

- At least 5 coughs during the second 30-minute period of the 60-minute baseline period.

General good health, aside from a common cold, and has no contraindications to the study or
rescue medication

Exclusion Criteria:

- Acute, subchronic, or chronic cough due to any other condition other than a common
cold

History of clinically significant cardiovascular, pulmonary, hepatic, renal, neurological,
hematological, autoimmune, psychiatric, metabolic, gastro-intestinal or endocrine disease