Bifidobacterium Lactis HN019 Supplementation for Prevention of Influenza Infection in Healthy Adults

Inclusion Criteria:

- Healthy free-living men and women aged 18 to 60 years

- Body mass index between 18.5 and 29.9 kg/m2 (encompasses normal weight and
overweight)

- Subject owns a refrigerator and is willing to keep study product refrigerated at all
times

- Ability of the participant (in the investigator's opinion) to comprehend the full
nature and purpose of the study, including possible risks and side effects

- Consent to the study and willing to comply with study product and methods

Exclusion Criteria:

- Influenza vaccination in last 6 months, or any other vaccination in previous 15 days

- Clinically significant underlying systemic illness that may preclude the subject's
ability to complete the trial

- Chronic nasal, laryngeal, pleural, or respiratory condition that could mimic or
obscure symptoms of influenza (e.g. chronic allergic rhinitis, asthma, COPD, as
determined by medical history and baseline physical examination)

- Chronic use of medication(s) that could suppress or prevent flu-like symptoms (eg,
antihistamines, cough medicines; echinacea, high-dose vitamin C)

- Use of medication(s) within the previous 3 months that affect immune response (eg,
antibiotics)

- Contraindication to dairy products or any other substance in the study product (eg,
lactose intolerance)

- History of alcohol, drug, or medication abuse

- Pregnant or lactating female, or pregnancy planned during study period

- Daily consumption of probiotics, prebiotics, fermented milk, and/or yogurt within 3
months of screening

- Participation in another study with any investigational product within 3 months of
screening

- Investigator believes that the participant may be uncooperative and/or noncompliant,
and should therefore not participate in the study