Treatment of Vitiligo With Low-energy Visible Light Laser

Vitiligo is a pigmentary disorder characterized by depigmented and hypopigmented macules and
patches. There are forms of vitiligo which are more resistant to treatment, including
segmental vitiligo and acral vitiligo. Previous studies have shown that a low energy
helium-neon (633 nm) laser can cause increased proliferation of melanocytes and
repigmentation in segmental-type vitiligo. The goal of this study is to verify these
results and show efficacy in other recalcitrant forms of vitiligo including acral vitiligo
and post melanocyte-keratinocyte transplantation vitiligo.

Inclusion Criteria:

- Be at least 18 years old

- Have active or stable segmental vitiligo on the neck or face, acral vitiligo, or have
undergone recent melanocyte-keratinocyte transplantation procedure (MKTP)

- Agree to abide by the Investigator's guidelines regarding photosensitizing drugs and
photoprotection

- Be able to understand the requirements of the study, the risks involved, and be able
to sign the informed consent form

- Agree to follow and undergo all study-related procedures

Exclusion Criteria:

- Women who are lactating, pregnant, or planning to become pregnant

- Patients with a recent history of melasma, and other disorders of pigmentation with
the exception of post inflammatory hyperpigmentation

- Patients with a known history of photosensitivity disorders

- Photosensitizing medications may be continued throughout of the study at the
discretion of the investigator

- Patients with a known history of melanoma or non-melanoma skin cancers

- Concomitant use of tanning beds

- Any reason the investigator feels the patient should not participate in the study