Study of Arthritis and Related Conditions



Status:Recruiting
Conditions:Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:Any
Updated:1/27/2019
Start Date:September 29, 2000
Contact:James D Katz, M.D.
Email:james.katz@nih.gov
Phone:(301) 451-6807

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Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions

This research protocol will recruit patients with arthritis and related conditions for the
purpose of screening patients for treatment protocols, and evaluating the natural history of
arthritis and related conditions. Patients will be evaluated clinically, radiographically and
serologically, and standardized data will be uniformly collected on all patients. Additional
imaging using sensitive MRI methods will be obtained in some patients. The collected blood
and tissue will be utilized for laboratory studies to continue research on the pathogenic
mechanisms of rheumatoid arthritis and related autoimmune joint diseases. Data from the
history and physical examination as well as several disability questionnaires in the adult
and pediatric population will be used to phenotypically characterize these patients and
assess outcome and functional status. Any medical care recommended or provided to the
patients will be consistent with routine standards of practice and provided in consultation
with the patient's referring physician.

This research protocol will recruit patients with arthritis and related conditions for the
purpose of screening patients for treatment protocols, and evaluating the natural history of
arthritis and related conditions. Patients will be evaluated clinically, radiographically and
serologically, and standardized data will be uniformly collected on all patients. Additional
imaging using sensitive MRI methods will be obtained in some patients. The collected blood
and tissue will be utilized for laboratory studies to continue research on the pathogenic
mechanisms of rheumatoid arthritis and related autoimmune joint diseases. Data from the
history and physical examination as well as several disability questionnaires in the adult
and pediatric population will be used to phenotypically characterize these patients and
assess outcome and functional status. Any medical care recommended or provided to the
patients will be consistent with routine standards of practice and provided in consultation
with the patient's referring physician.

- INCLUSION CRITERIA:

No age limits.

History of inflammatory synovitis of at least one or more swollen joints.

Patient's ability and willingness to give informed consent or in the pediatric patients,
the parent's willingness to give informed consent and the patient's willingness to assent
to the protocol whenever possible.

EXCLUSION CRITERIA:

None if patients fulfill inclusion criteria.
We found this trial at
1
site
9000 Rockville Pike
Bethesda, Maryland 20892
Phone: 800-411-1222
?
mi
from
Bethesda, MD
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