Transplant and Addiction Project (TAP) - 1

Participants who need a liver or renal transplant and who are ineligible due to current or
recent (past 6 months) alcohol and/or other drug abuse are being recruited from the
transplant programs at St. Luke's-Roosevelt Hospital Center (renal), Columbia Presbyterian
Hospital (renal/liver) and Virginia Commonwealth University Medical Center (liver). Baseline
and follow-up computer-assisted assessments and structured clinical interviews along with
collection of biological samples (urine, hair) will occur in the transplant clinics;
however, phone counseling sessions originate at St. Luke's. Participants are randomly
assigned to one of two treatments: (1) usual care (no phone counseling) or (2) usual care +
counseling. The telephone counseling sessions are designed to help participants become
motivated to remain abstinent and improve other health behaviors such as sleep or stress
management.

Inclusion Criteria:

- End stage liver or renal disease

- Having used drugs or alcohol during the past 6 months

- Turned down for transplant due to current or recent substance use

- Access to telephone

Exclusion Criteria:

- Psychotic or other unstable serious psychiatric disorders that preclude full, active
participation

- Moderate to severe hepatic encephalopathy

- Non-English speaking