Sensory Processing in Subjects With Painful Bladder Syndrome
| Status: | Completed |
|---|---|
| Conditions: | Pain, Urology |
| Therapuetic Areas: | Musculoskeletal, Nephrology / Urology |
| Healthy: | No |
| Age Range: | 19 - 75 |
| Updated: | 5/5/2014 |
| Start Date: | May 2008 |
| End Date: | June 2014 |
| Contact: | Timothy J Ness, MD, PhD |
| Email: | tjness@uab.edu |
| Phone: | 205-934-4665 |
The purpose of this study is to determine if clinically relevant subsets exist in patients
meeting the diagnosis of Painful Bladder Syndrome (PBS). Subsets suggest differential
responses to treatments and if verified, this will be important for the stratification of
patients in clinical studies related to PBS.
meeting the diagnosis of Painful Bladder Syndrome (PBS). Subsets suggest differential
responses to treatments and if verified, this will be important for the stratification of
patients in clinical studies related to PBS.
Patients with the diagnosis of painful bladder syndrome (PBS) constitute two or more
phenotypes that are distinguished by differential neurophysiological processing of sensory
information. Further, these differing phenotypes can be predicted by the presence or
absence of the co-morbidity fibromyalgia.
phenotypes that are distinguished by differential neurophysiological processing of sensory
information. Further, these differing phenotypes can be predicted by the presence or
absence of the co-morbidity fibromyalgia.
Inclusion Criteria:
- NIDDK criteria for Painful Bladder Syndrome
- Age 19 years or older
- Must be able to read and speak English since testing materials are validated in
English
Exclusion Criteria:
- PBS subjects must be independent of co-existing pain disorders or use of medications
- Uncontrolled hypertension or significant cardiopulmonary disease
- No chronic daily pain
- Older than 75 years of age
We found this trial at
1
site
Click here to add this to my saved trials
