Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin



Status:Completed
Conditions:Cancer, Brain Cancer, Cardiology, Endocrine
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology, Oncology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:September 2009
End Date:June 2015

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An Open Label, Multicenter, Single Arm Study of Pasireotide LAR in Patients With Rate Tumors of Neuroendocrine Origin

This study will assess the effectiveness and safety of pasireotide long-acting release in
patients who have rare tumors of neuroendocrine origin.


Inclusion Criteria:

- Male and Female Patients at least 18 years old

- Patient who have rare tumors of neuroendocrine origin, such as tumors of the:

1. pancreas

2. pituitary glands

3. Nelson syndrome

4. ectopic-ACTH secreting tumor

- Patients who have failed standard of care treatment or for whom no standard of care
treatment exist

- Signed Informed Consent

Exclusion Criteria:

- Patients with active gallbladder disease

- Patients with any ongoing or planned anti-neoplastic or interferon therapy

- Poorly controlled diabetes mellitus

- Female patients who are pregnant or lactating, or are of childbearing potential and
not practicing a medically acceptable method of birth control

Other protocol-defined inclusion/exclusion criteria may apply.
We found this trial at
7
sites
Stanford, California 94304
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Stanford, CA
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Boston, MA
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Buenos Aires,
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Los Angeles, CA
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Los Angeles, California 90048
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Los Angeles, CA
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New York, NY
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Seattle, WA
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