A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients



Status:Terminated
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:51 - 90
Updated:4/21/2016
Start Date:December 2009
End Date:November 2012

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A Phase 3 Extension, Multicenter, Long Term Safety And Tolerability Trial Of Bapineuzumab (Aab 001, Eln115727) In Subjects With Alzheimer Disease Who Are Apolipoprotein E 4 Carriers And Participated In Study 3133k1-3001-us Or Study 3133k1-3001-ww.

The purpose of this study is to assess the long-term safety and tolerability of bapineuzumab
in subjects with Alzheimer Disease who participated in study 3133K1-3001(NCT00676143). Over
250 sites will participate in over 26 countries. Subjects will receive bapineuzumab. Each
subject's participation will last approximately 4 years.


Inclusion Criteria:

- Subject has completed study 3133K1-3001 (Week 78) and brain magnetic resonance
imaging (MRI) scan consistent with the diagnosis of Alzheimer Disease

- Mini-Mental Status Examination (MMSE) >=10 at screening

- Caregiver able to attend all clinic visits with subject

Exclusion Criteria:

- Any medical or psychiatric contraindication or clinically significant abnormality
that, in the investigator's judgment, will substantially increase the risk associated
with the subject's participation in and completion of the study or could preclude the
evaluation of the subject's response.

- Any significant brain MRI abnormality.

- Use of any investigational drugs or devices, other than bapineuzumab within the last
60 days prior to screening
We found this trial at
64
sites
Raleigh, North Carolina 27607
371
mi
from 43215
Raleigh, NC
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1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
493
mi
from 43215
Birmingham, AL
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1000 Alpine
Boulder, Colorado 80304
303-443-7229
1175
mi
from 43215
Boulder, CO
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100 West Gore St # 202
Orlando, Florida 32806
(407) 426-9299
Compass Research LLC Compass Research is a clinical research company dedicated to testing new medications...
795
mi
from 43215
Orlando, FL
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5430 Fredericksburg Road
San Antonio, Texas 78229
210-377-2873
1137
mi
from 43215
San Antonio, TX
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3603 Paesanos Parkway
San Antonio, Texas 78231
210-614-4884
1132
mi
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San Antonio, TX
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Abington, Pennsylvania 19001
417
mi
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Abington, PA
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Abington, Pennsylvania 19001
418
mi
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Abington, PA
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Abington, Pennsylvania 19001
418
mi
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Abington, PA
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Atlantis, Florida 33462
940
mi
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Atlantis, FL
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Atlantis, Florida 33462
939
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Atlantis, FL
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Birmingham, Alabama 35294
492
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Birmingham, AL
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Boulder, Colorado 80304
1174
mi
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Boulder, CO
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5386
mi
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Buenos Aires,
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525
mi
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Charleston, SC
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
524
mi
from 43215
Charleston, SC
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Columbus, Ohio 43210
2
mi
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Columbus, OH
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Dallas, Texas 75214
907
mi
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Dallas, TX
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Delray Beach, Florida 33445
948
mi
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Delray Beach, FL
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Denver, Colorado 80218
1161
mi
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Denver, CO
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East Lansing, Michigan 48824
205
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East Lansing, MI
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East Providence, Rhode Island 02914
621
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East Providence, RI
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Eatontown, New Jersey 07724
473
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Eatontown, NJ
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293
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Elk Grove Village, IL
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520
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Fairfield, CT
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Goodyear, Arizona 85395
1678
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Goodyear, AZ
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Greenwich, Connecticut 06830
499
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Greenwich, CT
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Greenwich, Connecticut 06830
499
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Greenwich, CT
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Hattiesburg, Mississippi 39401
692
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Hattiesburg, MS
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Jenkintown, Pennsylvania 19046
418
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Jenkintown, PA
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Kansas City, Missouri 64114
620
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Kansas City, MO
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Lake Charles, Louisiana 70601
884
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Lake Charles, LA
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Lawrenceville, Georgia 30046
418
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Lawrenceville, GA
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Lawrenceville, Georgia 30046
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Lawrenceville, GA
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Little Rock, Arkansas 72205
624
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Little Rock, AR
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MDR
LiverPool, New York 13088
413
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LiverPool, NY
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Liverpool, New York 13088
413
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Liverpool, NY
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457
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Manchester, NJ
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North Charleston, South Carolina 29406
524
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North Charleston, SC
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Norwalk, Connecticut 06851
510
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Norwalk, CT
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922
mi
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Palm Beach Gardens, FL
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111 S 11th St
Philadelphia, Pennsylvania 19107
(215) 955-6000
Thomas Jefferson University Hospital Our hospitals in Center City Philadelphia share a 13-acre campus with...
416
mi
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Philadelphia, PA
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1020 Walnut St
Philadelphia, Pennsylvania 19107
(215) 955-6000
Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
416
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Philadelphia, PA
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Phoenix, Arizona 85006
1660
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Phoenix, AZ
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1661
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Phoenix, AZ
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Phoenix, Arizona 85032
1654
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Phoenix, AZ
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Phoenix, Arizona 85050
1651
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Phoenix, AZ
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Pittsfield, Massachusetts 01201
535
mi
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Pittsfield, MA
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Port Charlotte, Florida 33952
897
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Port Charlotte, FL
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Port Charlotte, Florida 33952
898
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Port Charlotte, FL
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Portland, Oregon 97210
2028
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Portland, OR
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2031
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Portland, OR
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Portland, Oregon 97225
2026
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Portland, OR
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Raleigh, North Carolina 27607
372
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Raleigh, NC
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Raleigh, North Carolina 27607
372
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Raleigh, NC
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Raleigh, North Carolina 27607
372
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Raleigh, NC
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San Antonio, Texas 78231
1132
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San Antonio, TX
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San Antonio, Texas 78258
1138
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San Antonio, TX
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San Francisco, California
2107
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San Francisco, CA
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Sarasota, Florida 34243
868
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Sarasota, FL
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351
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Springfield, IL
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Springfield, Massachusetts 01104
563
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Springfield, MA
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821
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Tampa, FL
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Toms River, New Jersey 08755
467
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Toms River, NJ
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