Prospective Analysis of Eosinophilic Esophagitis in Patients Presenting With Dysphagia
| Status: | Archived |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
This is a prospective descriptive cross sectional study to determine the percentage of
patients presenting with dysphagia who are found to have eosinophilic esophagitis (EoE) and
to establish which presenting factors warrant esophageal biopsies. We hypothesize that a
greater than expected percentage of patients who are biopsies will have histologic changes
consistent with EE.
All patients presenting with dysphagia who do not already carry a previous diagnosis for
their dysphagia will be asked to enroll. If patients have undergone previous work up for
dysphagia such as manometry, 24-hour probe, or barium swallow they can still participate in
this study. Informed consent will take place prior to enrollment. After patients present
with dysphagia they will fill-out a questionnaire regarding their dysphagia symptoms. An
EGD with biopsies will then be performed. Biopsies will be taken from 4 quadrants in the
proximal and distal esophagus. The distal esophagus biopsies will be taken 5 cm proximal to
the Z-line. Proximal biopsies will be taken anywhere proximal to 30 cm from the incisors.
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