Prognostic Value of Baseline Computed Tomography (CT) Perfusion Parameters of Pancreatic Cancer for Patients Undergoing Stereotactic Body Radiotherapy or Surgical Resection
| Status: | Terminated |
|---|---|
| Conditions: | Cancer, Cancer, Pancreatic Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 7/2/2016 |
| Start Date: | March 2010 |
| End Date: | June 2012 |
Prognostic Value of Baseline CT Perfusion Parameters of Pancreatic Cancer for Patients Undergoing Stereotactic Body Radiotherapy or Surgical Resection
The purpose of this study is first, to determine whether baseline perfusion characteristics
of pancreatic cancer, as characterized by CT perfusion studies, can predict tumor response
to treatment by stereotactic body radiotherapy (SBRT). The second goal of this study is to
determine whether baseline perfusion characteristics in those patients with resectable
pancreatic cancer correlate with immunohistologic markers of angiogenesis such as
microvessel density and vascular endothelial growth factor (VEGF) expression.
of pancreatic cancer, as characterized by CT perfusion studies, can predict tumor response
to treatment by stereotactic body radiotherapy (SBRT). The second goal of this study is to
determine whether baseline perfusion characteristics in those patients with resectable
pancreatic cancer correlate with immunohistologic markers of angiogenesis such as
microvessel density and vascular endothelial growth factor (VEGF) expression.
Inclusion Criteria:
1. suspected and/or biopsy-proven pancreatic adenocarcinoma, and
2. referral to Radiology for pre-treatment baseline pancreatic protocol CT.
Exclusion criteria:
1) are absolute contraindications to intravenous iodinated contrast or CT scan.
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Stanford University School of Medicine Vast in both its physical scale and its impact on...
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