Use of Dexmedetomidine for Deep Sedation in Patients Undergoing Outpatient Hysteroscopic Surgery
| Status: | Recruiting |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 9/23/2012 |
| Start Date: | October 2010 |
| Contact: | Shireen Ahmad, MD |
| Email: | sah704@northwestern.edu |
| Phone: | 312-472-0550 |
Patients undergoing deep sedation for outpatient procedures typically receive a combination
of benzodiazepines, propofol, and opioids. Side effects of such anesthetics include
respiratory depression, nausea and vomiting, and urinary retention, with resultant extended
hospital stays and unanticipated admission. The use of dexmedetomidine for deep sedation
may increase patient safety by maintaining respiratory drive, while providing sedation,
hypnosis, and analgesia. Furthermore, patients may experience decreased pain, nausea, and
time to discharge in the PACU, especially if dexmedetomidine decreases the requirement of
other drugs such as opioids.
The hypothesis of this study is administration of dexmedetomidine during deep sedation for
ambulatory hysteroscopic surgery will result in a 50% reduction of intraoperative opioid
compared to sedation with propofol.
Inclusion Criteria:
- ASA I-II
- Age: 18-64 years
- Female
- Surgery: Gynecologic hysteroscopy
- Language: English speaking
- Consent: Obtained
Exclusion Criteria:
- Pregnant or breast feeding
- Significant arrhythmia or high degree atrioventricular nodal block
- Significant hepatic or renal dysfunction
- Chronic use or addiction to opiates or sedatives
- History of heavy alcohol usage (>4 drinks/day)
- Psychiatric or emotional disorder
- Chronic use of α2-agonists
- Patients with OSA or BMI greater than 30
- Allergy to study drug or anesthetic medications utilized in the protocol
We found this trial at
1
site
Click here to add this to my saved trials
