Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 4/2/2016 |
| Start Date: | March 2011 |
| End Date: | June 2012 |
| Contact: | Evan Goodman, MD |
| Email: | evan.goodman@uhhospitals.org |
| Phone: | 2168445300 |
A Comparison of Single Dose Preservative Free Morphine With Fentanyl Infusion for Post-Cesarean Section Analgesia
For post-Cesarean analgesia, the investigators will compare the efficacy of single-shot
epidural preservative free morphine with a continuous epidural fentanyl infusion. The
investigators will be comparing the patient's pain level and satisfaction with the two
techniques, as well as the side effects that the patients experience, such as itching,
nausea, back pain and respiratory depression.
epidural preservative free morphine with a continuous epidural fentanyl infusion. The
investigators will be comparing the patient's pain level and satisfaction with the two
techniques, as well as the side effects that the patients experience, such as itching,
nausea, back pain and respiratory depression.
Included in the study will be all healthy (ASA I or II) woman having elective Cesarean
sections who are candidates for regional anesthesia. Exclusion criteria include morbid
obesity (BMI > 40), age less that 18 years, history of sleep apnea, and abuse of or
intolerance to opioid analgesics.
All patients will also receive 100 micrograms of fentanyl once epidurally during the
Cesarean section, and they will receive ibuprofen every six hours for the first 24 hours
after the Cesarean section. The patients will be visited twice a day postoperatively for two
days. The epidural morphine will be expected to last only approximately 20 hours, while the
fentanyl infusion will be kept in place for two days after the procedure. Additional
analgesics, such as intravenous morphine or PO oxycodone and tylenol, will be available for
breakthrough pain.
sections who are candidates for regional anesthesia. Exclusion criteria include morbid
obesity (BMI > 40), age less that 18 years, history of sleep apnea, and abuse of or
intolerance to opioid analgesics.
All patients will also receive 100 micrograms of fentanyl once epidurally during the
Cesarean section, and they will receive ibuprofen every six hours for the first 24 hours
after the Cesarean section. The patients will be visited twice a day postoperatively for two
days. The epidural morphine will be expected to last only approximately 20 hours, while the
fentanyl infusion will be kept in place for two days after the procedure. Additional
analgesics, such as intravenous morphine or PO oxycodone and tylenol, will be available for
breakthrough pain.
Inclusion Criteria:
- Patients having an elective Cesarean section
- Healthy women (ASA I or II)
- Regional anesthesia candidates
Exclusion Criteria:
- Morbid obesity (BMI>40)
- Sleep apnea
- Age under 18
- Intolerance or addiction to opioids
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