Effectiveness of Smoking-cessation Interventions for Urban Hospital Patients

Our sites are: Bellevue Hospital Center (a New York City public hospital) and the Manhattan
campus of the VA New York Harbor Healthcare System. During hospitalization, all smokers will
receive usual care. At the time of discharge, patients will be randomized to one of two
arms: multisession telephone counseling by their hospital's smoking cessation staff, or
faxed referral to the state Quitline (which will then perform phone outreach as per Quitline
protocol). All patients enrolled in the study will receive nicotine replacement therapy.

The primary aims are:

Aim 1: To compare the effectiveness of the intervention (proactive multisession telephone
counseling by in-hospital staff) versus control ('fax-to-quit' Quitline referral).

Aim 2: To evaluate and compare the cost-effectiveness of these interventions from a societal
perspective and from a payer perspective.

The secondary aims are:

Secondary Aim 1: To compare outcomes by race/ethnicity, immigrant status, inpatient
diagnosis, and location of patient hospitalization Secondary Aim 2: To compare outcomes of
the interventions at 6 and 12 months post-discharge Secondary Aim 3: To compare
biochemically-verified abstinence rates at 6 months post-discharge Secondary Aim 4: To
compare cessation outcomes between those who are known HIV-seropositive and those who are
not, and explore possible mediators of cessation in HIV-seropositive patients

Inclusion Criteria:

- age ≥ 18 years

- smoked tobacco during the prior 30 days

- have an active phone number

- provide consent in English, Spanish or Mandarin

Exclusion Criteria:

- Patients will be excluded if they use only smokeless tobacco or products such as
betel (since there is not yet efficacy data for treating use of these tobacco
products in the inpatient setting)

- are pregnant or breastfeeding

- are discharged to an institution (e.g. jail/prison, nursing home, long-term
psychiatric facility).