Hypofractionated Proton Radiation Therapy for Low and Intermediate Risk Prostate Cancer



Status:Active, not recruiting
Conditions:Prostate Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:9/26/2018
Start Date:September 2011
End Date:September 2036

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Trial Summary
Trial Overview
Inclusion Criteria

An Expanded Phase II Study of Hypofractionated Dose Intense Image Guided Proton Radiation Therapy for Low and Intermediate Risk Adenocarcinoma of the Prostate

The purpose of this trial is to give a shorter course (5 ½-6 weeks) of proton radiation that
has as little side effects on normal bladder and rectal tissues as the usual longer course (8
weeks) of proton radiation, without decreasing the chance of killing prostate cancer cells.


Inclusion Criteria:

- Prostate cancer.

- Gleason score 2-6 or 7.

- PSA ≤ 20 ng/ml.

Exclusion Criteria:

- Previous prostate cancer surgery or pelvic radiation.

- Prior/concurrent systemic chemotherapy for prostate cancer.

- Active inflammatory bowel disease (Crohn's disease, diverticulitis or ulcerative
colitis) affecting the rectum.

- History of hip replacement.

- Prior intrapelvic surgery.

- Taking Saw Palmetto or methotrexate and unable or unwilling to discontinue its uses
during radiation.

- Receiving continuous and current anticoagulation with Warfarin sodium (Coumadin),
Clopidogrel bisulfate (Plavix), dabigatran etexilate mesylate (Pradaxa),enoxaparin
sodium (Lovenox), or aspirin/er dipyridamole (Aggrenox).
We found this trial at
1
site
University of Florida Proton Therapy Institute
2015 Jefferson St
Jacksonville, Florida 32206
(904) 588-1800
University of Florida Proton Therapy Institute When the University of Florida Proton Therapy Institute opened...
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mi
from
Jacksonville, FL
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