Long-Term Growth and Skeletal Effects of Early Growth Hormone Treatment in Turner Syndrome
| Status: | Completed |
|---|---|
| Conditions: | Other Indications |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 4 - 20 |
| Updated: | 4/21/2016 |
| Start Date: | December 2005 |
| End Date: | September 2015 |
Effect of Early Growth Hormone Treatment on Long-term Growth and Skeletal Maturation in Girls With Turner Syndrome
This is an extension study that will gather long-term data on the effect of early growth
hormone (GH) treatment on adult height and other aspects of health and development in girls
with Turner syndrome. The main purpose is to determine whether girls who received 2 years of
GH treatment before 6 years of age achieve taller adult height than girls who were untreated
during this time. The study will also look at middle ear and hearing function, and cognitive
and behavioral development. Protocol completion is defined as attainment of height velocity
less than or equal to 1.0 cm/year, or bone age greater than or equal to 15 years.
hormone (GH) treatment on adult height and other aspects of health and development in girls
with Turner syndrome. The main purpose is to determine whether girls who received 2 years of
GH treatment before 6 years of age achieve taller adult height than girls who were untreated
during this time. The study will also look at middle ear and hearing function, and cognitive
and behavioral development. Protocol completion is defined as attainment of height velocity
less than or equal to 1.0 cm/year, or bone age greater than or equal to 15 years.
Inclusion Criteria:
- Previously randomized in study B9R-US-GDFG
- Karyotype-proven Turner syndrome
Exclusion Criteria:
- Immediate family members of study site personnel directly affiliated with the study
We found this trial at
9
sites
Childrens Hospital Los Angeles Children's Hospital Los Angeles is a 501(c)(3) nonprofit hospital for pediatric...
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Connecticut Children's Medical Center Connecticut Children’s Medical Center is a nationally recognized, 187-bed not-for-profit children’s...
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Children's Mercy Hospital Children's Mercy Hospitals and Clinics continues redefining pediatric medicine throughout the Midwest...
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Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
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