Objective Evaluation of Ocular Surface Lubricants in Two Environments

This study will objectively evaluate ocular surface lubricants in subjects with dry eye
syndrome. Lubricants contain compounds that are purported to improve dry eye symptoms,
although objective data is not available. The investigators seek to objectively evaluate the
effectiveness of two lubricants and compare the results to a saline eye drop (control).

The investigators will assess the tear film and lipid layer before and after the
administration of three products in the same eye of 25 dry eye subjects using wavefront
sensing, ellipsometry, and thermal imaging in a "normal" environment. Subsequently the
investigators will change the environment to one that causes the subjects' ocular surface to
experience "evaporative stress" (warmer, less humid and greater air flow) and perform the
before and after drop administration measurements with the same three products in the same
eye as the first environment.

Inclusion Criteria:

- Age 30-75 years

- Good general health

- Willing to spend time for the study; approximately one hour for a screening visit
and 90 minutes for each of the measurement visits

- Currently using an OTC artificial tear for ocular comfort, at least occasionally.

- At least one positive dry eye symptom.

Exclusion Criteria:

- Current eye disease, infection or inflammation that requires the use of any
prescription ocular medication.

- Recent past eye surgery.

- Female subjects may not be pregnant or lactating.

- Infectious diseases