The PERFusion Use in Stroke Evaluation Study
| Status: | Recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease, Neurology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Neurology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/17/2019 |
| Start Date: | May 2011 |
| End Date: | January 2021 |
Expanding the Time Window for IV Thrombolysis With Rt-PA in Acute Ischemic Stroke Patients Using Computed Tomography Perfusion Imaging: The PERFusion Use in Stroke Evaluation (PERFUSE) Study
This is an open label single center phase II trial, evaluating the utility of 64 slice CT
perfusion (CTP) in acute ischemic stroke (AIS) patients. The main aim is to determine which
aspects of CTP imaging can aid in expanding the time window for thrombolysis with IV (rt-PA)
in AIS patients up to 6 hours after symptom onset.
perfusion (CTP) in acute ischemic stroke (AIS) patients. The main aim is to determine which
aspects of CTP imaging can aid in expanding the time window for thrombolysis with IV (rt-PA)
in AIS patients up to 6 hours after symptom onset.
Inclusion Criteria:
- Acute ischemic stroke
- ≥ 18 years old
- presentation up to 6 hours from time of onset of acute stroke symptoms
Exclusion Criteria:
- pregnancy
- inability to receive CT scan
- allergy to IV contrast
- symptoms with full resolution
- intracerebral hemorrhage
- severe stroke which is classified as 'malignant' (hypodensity on noncontrast CT
greater than 1/3 cerebral hemisphere)
- premorbid mRS of >3
- life expectancy of ≤3 months
- any condition which, in the opinion of the investigator makes the subject unsuitable
for study
We found this trial at
1
site
45 Castro Street
San Francisco, California 94114
San Francisco, California 94114
(415) 600-6000
Principal Investigator: Nobl Barazangi, MD PhD
Phone: 415-600-5721
California Pacific Medical Center California Pacific Medical Center is one of the largest private, not-for-profit,...
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