Effects of Dronabinol (Oral THC) on Cannabis Use
| Status: | Completed |
|---|---|
| Conditions: | Smoking Cessation, Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 100 |
| Updated: | 8/4/2017 |
| Start Date: | February 2011 |
| End Date: | September 2012 |
Study participants received dronabinol (0, 120mg/day and 240mg/day) for 12 consecutive days
in a randomized order. During each dronabinol maintenance period they were able to
self-administer active or placebo cannabis using either a progressive ratio schedule or
choice between cannabis and monetary alternative.
in a randomized order. During each dronabinol maintenance period they were able to
self-administer active or placebo cannabis using either a progressive ratio schedule or
choice between cannabis and monetary alternative.
Inclusion Criteria:
- Current use of marijuana
- Able to give informed consent
Exclusion Criteria:
- Daily use of psychoactive medication
- Current Axis I psychiatric disorder other than dependence on cannabis or nicotine, or
abuse of drugs or alcohol
- Women who are pregnant, breast feeding, or planning to become pregnant within the next
3 months
- Those seeking treatment for cannabis-related problems or using cannabis under the
guidance of a physician for a medical disorder
- Uncontrolled or unstable cardiovascular disease
- Allergy to sesame oil
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