Electrocardiographic Mapping and Imaging
| Status: | Completed |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/19/2013 |
| Start Date: | June 2012 |
| End Date: | July 2013 |
The purpose of this study is to evaluate a novel non-invasive cardiac electric imaging
methodology for localizing and imaging cardiac electrical activity from body surface
electrocardiographic recordings in patients with ventricular tachycardia (VT). Using
non-invasive means will increase our ability to correctly diagnose cardiac abnormalities,
and aid ablation of cardiac arrhythmias, offering enhanced performance to what currently
exists.
Specific Aims
1. Use non-invasive cardiac electric imaging to provide information as to the sites of
origin of arrhythmias and sequence of cardiac activation and repolarization.
Methods and Procedures Approximately 8 patients with recorded Premature Ventricular
Contractions (PVC), Wolff-Parkinson-White (WPW) or other ventricular tachycardia cases which
need Ensite/Carto endocardial mapping and radiofrequency ablation treatment will be
enrolled.
One day before catheterization and ablation, patients will undergo approximately 30 minutes
of Body Surface Potential Mapping (BSPM) recordings with about 200 surface electrodes
arranged in 20 strips, attached on his/her front and back. BSPMs will be recorded in the
baseline resting rhythm.
On the day of ablation, before catheterization in the surgical room, the BSPM recording
procedure will be carried out with the patient using the same technique used during the
first BSPM study.
Clinical endocardial mapping data may also be obtained concurrently with BSPM recordings
before the ablation procedure.
Another BSPM recording will be made 30-60 minutes after successful ablation with the patient
still in normal sinus rhythm if possible. Patients will be followed up 1 month after
ablation with the same method of BSPM recorded at the baseline resting rhythm.
Any patient undergoing ablation.
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