Menstrual Cycle Hormones and Eating Behavior



Status:Completed
Conditions:Food Studies
Therapuetic Areas:Pharmacology / Toxicology
Healthy:No
Age Range:18 - 35
Updated:12/7/2017
Start Date:March 2011
End Date:December 2012

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Effect of Menstrual Cycle Hormone Changes on Eating Behavior and Nutrient Metabolism

The purpose of this study is to determine if the phase of the menstrual cycle (opposed versus
unopposed estrogen phase) affects eating behavior, including types of foods preferred,
wanting/desire for specific foods, and perception of hunger.

This is an observational study to investigate the effect of endogenous estrogen (E2) and
progesterone (P4) levels on eating behavior and energy-yielding nutrient metabolism. Eating
behavior will be assessed during a complete menstrual cycle during the first month of the
study. Participants will track the follicular and luteal phases of their menstrual cycle
using urinary leuteinizing hormone (LH) kits, they will record information about their food
intake, eating behaviors, and appetite in their home environments, and they will complete two
laboratory test days: one test day scheduled during their follicular phase, and one test day
scheduled during their luteal phase.

Inclusion Criteria:

- Body Mass Index between 20-30 Kg/m2

- regular menstrual cycles

- sedentary lifestyle (physical activity not more than 30 minutes per day three times a
week)

Exclusion Criteria:

- Fasting blood sugar greater than 110 mg/dL

- Systolic Blood Pressure greater than 140 mmHg

- Diastolic Blood Pressure greater than 90 mmHg

- Fasting triglycerides greater than 120 mg/dL

- Documented or self-reported chronic disorders such as arthritis, or other inflammatory
diseases

- Women who are Post-menopausal or Peri-menopausal

- Pre-menopausal women who are pregnant, uni/multiparous, taking oral contraceptives, or
who have menstrual cycles lasting less than 20 days or greater than 45 days,
polycystic ovary syndrome (PCOS), amenorrhea, eumenorrhoea, or polymenorrhoea.
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