Occult Gastrointestinal Bleeding in Non-pulsatile Left Ventricular Assist Device(VAD)Patients
| Status: | Completed |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | July 2011 |
| End Date: | July 2014 |
| Contact: | Jonathan Wright |
| Email: | Wright.Jonathan@mayo.edu |
| Phone: | 905-953-7521 |
The purpose of this study is to estimate the proportion of Ventricular Assist Device (VAD)
patients with abnormal gastrointestinal bleeding as assessed by HemoQuant fecal occult blood
test. Also, in patients with gastrointestinal bleeding present, to summarize the extent of
gastrointestinal bleeding; to examine the behavior of HemoQuant fecal occult blood test over
time by estimating the proportion of VAD patients with a positive test prior to
implantation; at one week, one month, three months, six months and one year post
implantation, and after explantation of the VAD and to evaluate whether presence of any
abnormal fecal HemoQuant test is predictive of a future major bleeding event.
patients with abnormal gastrointestinal bleeding as assessed by HemoQuant fecal occult blood
test. Also, in patients with gastrointestinal bleeding present, to summarize the extent of
gastrointestinal bleeding; to examine the behavior of HemoQuant fecal occult blood test over
time by estimating the proportion of VAD patients with a positive test prior to
implantation; at one week, one month, three months, six months and one year post
implantation, and after explantation of the VAD and to evaluate whether presence of any
abnormal fecal HemoQuant test is predictive of a future major bleeding event.
Inclusion Criteria:
- Group 1 - cross sectional study. Patients with implanted non-pulsatile ventricular
assist devices of any type and at any time after implantation
- Group 2 - prospective study. Patients with usual VAD indications will be invited to
participate, when, in the opinion of their treating physician a VAD will be highly
likely within one month.
Exclusion Criteria:
- Unwillingness to provide stool samples for study
- Unwillingness to be followed for study endpoints.
- Unwillingness to follow dietary restrictions necessary for accurate HemaQuant
measurement
We found this trial at
2
sites
Click here to add this to my saved trials
Mayo Clinic Mayo Clinic's campus in Arizona provides medical care for thousands of people from...
Click here to add this to my saved trials