Alzheimer's Disease Core Center
| Status: | Recruiting |
|---|---|
| Conditions: | Alzheimer Disease, Cognitive Studies |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 4/2/2016 |
| Start Date: | July 2001 |
| End Date: | July 2025 |
Arizona Alzheimer's Disease Core Center
The main objective of this research project is to provide a comprehensive clinical database
of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild
cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to
identify cognitively normal individuals at genetically defined risk for Alzheimer's disease
through genetic screening.
All participants are seen annually. Autopsies to establish diagnoses in patients with
dementia, patients with mild MCI, and cognitively normal elderly control subjects will also
be conducted.
of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild
cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to
identify cognitively normal individuals at genetically defined risk for Alzheimer's disease
through genetic screening.
All participants are seen annually. Autopsies to establish diagnoses in patients with
dementia, patients with mild MCI, and cognitively normal elderly control subjects will also
be conducted.
All participants are seen annually. In addition to a detailed neurological examination,
participants will receive a standardized battery of neuropsychological tests and will
undergo genetic testing. The investigators will provide standardized periodic longitudinal
assessment of the research participants. Autopsies to establish neurohistopathological
diagnoses in clinically well-characterized patients with dementia, patients with mild MCI,
and cognitively normal elderly control subjects will also be conducted.
participants will receive a standardized battery of neuropsychological tests and will
undergo genetic testing. The investigators will provide standardized periodic longitudinal
assessment of the research participants. Autopsies to establish neurohistopathological
diagnoses in clinically well-characterized patients with dementia, patients with mild MCI,
and cognitively normal elderly control subjects will also be conducted.
Inclusion Criteria:
For patients with MCI, or dementia, the presence of cognitive deficits including memory,
language, and executive function.
Exclusion Criteria:
Presence of non-neurological medical conditions interfering with cognition.
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