Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease



Status:Completed
Conditions:Renal Impairment / Chronic Kidney Disease
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:Any
Updated:2/4/2013
Start Date:June 2011
End Date:June 2014
Contact:OVERTURE Study Info
Email:OVERTUREStudyInfo@mmgct.com

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A Multi-center, Longitudinal, Observational Study of Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) to Establish the Rate, Characteristics, and Determinants of Disease Progression


To collect characteristics of patients with ADPKD across a broad population, over time to
better understand disease progression (signs, symptoms and outcomes). Association with
total kidney volume changes and other measures of disease progression will be determined in
order to identify a population at increased risk for disease progression. The economic and
quality life impact of ADPKD will be assessed. Subjects who terminated participation early
from clinical trials with tolvaptan may also be followed.


Inclusion Criteria:

- existing diagnosis of ADPKD by modified-Ravine criteria

- Total kidney volume >= 300 cc/m height by ultrasound or >= 250 cc/m height by MRI

Exclusion Criteria:

- Current or expected (within the next six months) interventions for the treatment of
ADPKD affecting kidney volume
We found this trial at
37
sites
Providence, Rhode Island 02903
1424
mi
from
Providence, RI
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Alburquerque, New Mexico 87102
523
mi
from
Alburquerque, NM
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Azusa, California 91702
1148
mi
from
Azusa, CA
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Baltimore, Maryland 21215
1148
mi
from
Baltimore, MD
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Bluefield, West Virginia 24701
909
mi
from
Bluefield, WV
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Bronx, New York 10461
1295
mi
from
Bronx, NY
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Burlington, Vermont 05401
1356
mi
from
Burlington, VT
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Chapel Hill, North Carolina 27599
1043
mi
from
Chapel Hill, NC
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Chicago, Illinois 60637
610
mi
from
Chicago, IL
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Cincinnati, Ohio 45224
726
mi
from
Cincinnati, OH
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Denver, Colorado 80210
409
mi
from
Denver, CO
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Fairfax, Virginia 22030
1113
mi
from
Fairfax, VA
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Fargo, North Dakota 58122
632
mi
from
Fargo, ND
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Galveston, Texas 77555
609
mi
from
Galveston, TX
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Holyoke, Massachusetts 01040
1364
mi
from
Holyoke, MA
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Huntsville, Alabama 35802
659
mi
from
Huntsville, AL
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Jacksonville, Florida 32216
1055
mi
from
Jacksonville, FL
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Kansas City, Kansas 66160
196
mi
from
Kansas City, KS
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Las Vegas, Nevada 89106
960
mi
from
Las Vegas, NV
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Lexington, Kentucky 40504
725
mi
from
Lexington, KY
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Madison, Wisconsin 53705
575
mi
from
Madison, WI
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Meridian, Idaho 83642
1050
mi
from
Meridian, ID
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Mount Laurel, New Jersey 08054
1239
mi
from
Mount Laurel, NJ
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Nashville, Tennessee 37205
619
mi
from
Nashville, TN
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New Haven, Connecticut 06510
1344
mi
from
New Haven, CT
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Orangeburg, South Carolina 29118
995
mi
from
Orangeburg, SC
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Peoria, Arizona 85381
858
mi
from
Peoria, AZ
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Philadelphia, Pennsylvania 19102
1225
mi
from
Philadelphia, PA
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Portland, Oregon 97210
1383
mi
from
Portland, OR
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Rapid City, South Dakota 57701
520
mi
from
Rapid City, SD
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Rochester, Minnesota 55905
515
mi
from
Rochester, MN
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Saginaw, Michigan 48602
823
mi
from
Saginaw, MI
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Savannah, Georgia 31405
1023
mi
from
Savannah, GA
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Shreveport, Louisiana 71101
428
mi
from
Shreveport, LA
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Springfield, Massachusetts 01107
1364
mi
from
Springfield, MA
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St. Louis, Missouri 63110
418
mi
from
St. Louis, MO
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Washington, District of Columbia 20010
1127
mi
from
Washington,
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