Sleep Patterns in Children With and Without Juvenile Idiopathic Arthritis
| Status: | Completed |
|---|---|
| Conditions: | Arthritis |
| Therapuetic Areas: | Rheumatology |
| Healthy: | No |
| Age Range: | 6 - 11 |
| Updated: | 4/2/2016 |
| Start Date: | September 2011 |
| End Date: | February 2015 |
| Contact: | Teresa M Ward, PhD, RN |
| Email: | teward@u.washington.edu |
| Phone: | 206-221-6576 |
The investigators are doing this study to look at sleep problems, daytime sleepiness, and
thinking and behavior patterns in children with arthritis and in children without arthritis.
Arthritis is a problem with joints. Some children have arthritis and some children do not
have arthritis.
Sleep disordered breathing is a sleeping problem in which some children snore and have
pauses in their breathing during sleep. It is associated with not enough or fragmented
sleep, poor school performance, problems paying attention, and behavior problems.
The investigators do not know how many children with arthritis have sleep problems, and how
it is linked to daytime sleepiness and children's learning, and behavior patterns compared
to children without arthritis. The investigators need to study both children with arthritis
and children without arthritis to learn more about these connections and to understand if
they are the same or different in children with arthritis and in children without arthritis.
thinking and behavior patterns in children with arthritis and in children without arthritis.
Arthritis is a problem with joints. Some children have arthritis and some children do not
have arthritis.
Sleep disordered breathing is a sleeping problem in which some children snore and have
pauses in their breathing during sleep. It is associated with not enough or fragmented
sleep, poor school performance, problems paying attention, and behavior problems.
The investigators do not know how many children with arthritis have sleep problems, and how
it is linked to daytime sleepiness and children's learning, and behavior patterns compared
to children without arthritis. The investigators need to study both children with arthritis
and children without arthritis to learn more about these connections and to understand if
they are the same or different in children with arthritis and in children without arthritis.
Overview of Study:
- Children and their parent will be scheduled to come to the University of Washington
School of Nursing Sleep Laboratory for overnight polysomnography, and to complete
multi-sleep latency tests and a battery of neurobehavioral performance tests the next
day at a convenient time and day.
- Children will be asked to complete a sleep, symptoms (pain, fatigue), behavior, and day
to day activity surveys, and the parent who accompanies the child to the laboratory,
will be asked to complete surveys assessing demographics, child's usual sleep,
behavior, school performance, health status, and family functioning.
- Children will also be asked to spit in a container and urinate in a container upon
awakening in the morning after their sleep study.
Primary Aims of the Study:
1. Compare indices of sleep disturbances, risk factors, and type of sleep disordered
breathing(primary snoring, upper airway resistance syndrome, obstructive sleep apnea)
in Juvenile Idiopathic Arthritis (JIA) to age, sex matched control children.
2. Compare scores on neurobehavioral tests and daytime sleepiness; and to describe
associations between indices of sleep disturbances on neurobehavioral performance and
daytime sleepiness in JIA to age, sex matched control children.
Secondary Objectives:
1. Describe and compare parent report of child's sleep habits, fatigue, behavior, school
performance, day-to-day activity, and family functioning in children with JIA to age, sex
matched control children.
- Children and their parent will be scheduled to come to the University of Washington
School of Nursing Sleep Laboratory for overnight polysomnography, and to complete
multi-sleep latency tests and a battery of neurobehavioral performance tests the next
day at a convenient time and day.
- Children will be asked to complete a sleep, symptoms (pain, fatigue), behavior, and day
to day activity surveys, and the parent who accompanies the child to the laboratory,
will be asked to complete surveys assessing demographics, child's usual sleep,
behavior, school performance, health status, and family functioning.
- Children will also be asked to spit in a container and urinate in a container upon
awakening in the morning after their sleep study.
Primary Aims of the Study:
1. Compare indices of sleep disturbances, risk factors, and type of sleep disordered
breathing(primary snoring, upper airway resistance syndrome, obstructive sleep apnea)
in Juvenile Idiopathic Arthritis (JIA) to age, sex matched control children.
2. Compare scores on neurobehavioral tests and daytime sleepiness; and to describe
associations between indices of sleep disturbances on neurobehavioral performance and
daytime sleepiness in JIA to age, sex matched control children.
Secondary Objectives:
1. Describe and compare parent report of child's sleep habits, fatigue, behavior, school
performance, day-to-day activity, and family functioning in children with JIA to age, sex
matched control children.
Inclusion Criteria:
Children
- Children with and without arthritis, 6 thru 11 years old, able to speak English
- Children with JIA not recently hospitalized for severe JIA.
Parents
- Subject's parents or legal guardian are > 18 years of age and able to read and speak
English.
- Subject's parent or legal guardian has provided written informed consent prior to
screening for this study.
Exclusion Criteria:
Children
- A child with a history of/current diagnosis of a psychiatric condition meeting
DSM-IV-TR (e.g. depression, bipolar disorder) that would interfere with ability to
comply with protocol requirements, or give informed consent, or be expected to have
disordered sleep.
- A child with acute illness such as a cold or the flu that would interfere with sleep
and neurobehavioral testing.
- A chronic condition such as cancer, diabetes, or asthma which would, in the
investigator's opinion, compromise the subject's ability to comply with the study
requirements and interfere with ability to comply with protocol requirements.
- Children admitted to the hospital for severe JIA within the last 2 months.
- Children with a BMI >95th percentile (defined as obesity by CDC) will be excluded
because of potential impact of obesity on SDB.
Parents
- A parent or legal guardian with a chronic condition that would compromise the
parent's ability to comply with protocol requirements.
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