Open Label Study of Long Term Evaluation Against LDL-C Trial



Status:Completed
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 75
Updated:11/4/2018
Start Date:October 7, 2011
End Date:June 20, 2018

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Multicenter, Controlled, Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of AMG 145 (Evolocumab)

The primary clinical hypothesis is that long-term exposure of evolocumab (AMG 145) will be
safe and well tolerated in subjects with hypercholesterolemia.


Inclusion Criteria:

- Complete a qualifying evolocumab (AMG 145) parent study protocol

Exclusion Criteria:

- Experienced a treatment-related serious adverse event that led to IP discontinuation
in the parent study

- Have an unstable medical condition, in the judgment of the investigator

- Known sensitivity to any of the products to be administered during dosing

- Currently enrolled in another investigational device or drug study (excluding
evolocumab (AMG 145) parent study), or less than 30 days since ending another
investigational device or drug study(s),or receiving other investigational agent(s)
We found this trial at
70
sites
Clinical Trial Facility in Melbourne Florida
Melbourne, Florida
?
mi
from
Melbourne, FL
Click here to add this to my saved trials
Clinical Trial Facility in Akron Ohio
Akron, Ohio
?
mi
from
Akron, OH
Click here to add this to my saved trials
Clinical Trial Facility in Anaheim California
Anaheim, California 92801
?
mi
from
Anaheim, CA
Click here to add this to my saved trials
Clinical Trial Facility in Arlington Texas
Arlington, Texas 76017
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Clinical Trial Facility in Atlanta Georgia
Atlanta, Georgia
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Clinical Trial Facility in Auburn Maine
Auburn, Maine 04210
?
mi
from
Auburn, ME
Click here to add this to my saved trials
Clinical Trial Facility in Bethesda Maryland
Bethesda, Maryland
?
mi
from
Bethesda, MD
Click here to add this to my saved trials
Clinical Trial Facility in Birmingham Alabama
Birmingham, Alabama
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Clinical Trial Facility in Bristol Tennessee
Bristol, Tennessee 37620
?
mi
from
Bristol, TN
Click here to add this to my saved trials
Clinical Trial Facility in Brockton Massachusetts
Brockton, Massachusetts 02301
?
mi
from
Brockton, MA
Click here to add this to my saved trials
Clinical Trial Facility in Brooklyn Center Minnesota
Brooklyn Center, Minnesota 55430
?
mi
from
Brooklyn Center, MN
Click here to add this to my saved trials
Clinical Trial Facility in Cadiz Ohio
Cadiz, Ohio 43907
?
mi
from
Cadiz, OH
Click here to add this to my saved trials
Clinical Trial Facility in Camp Hill Pennsylvania
Camp Hill, Pennsylvania 17011
?
mi
from
Camp Hill, PA
Click here to add this to my saved trials
Clinical Trial Facility in Camperdown New South Wales
Camperdown, New South Wales 2050
?
mi
from
Camperdown,
Click here to add this to my saved trials
Clinical Trial Facility in Carmichael California
Carmichael, California 95608
?
mi
from
Carmichael, CA
Click here to add this to my saved trials
Clinical Trial Facility in Chevy Chase Maryland
Chevy Chase, Maryland 20815
?
mi
from
Chevy Chase, MD
Click here to add this to my saved trials
Clinical Trial Facility in Chicago Illinois
Chicago, Illinois
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Clinical Trial Facility in Cincinnati Ohio
Cincinnati, Ohio
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Clinical Trial Facility in Cleveland Ohio
Cleveland, Ohio
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Clinical Trial Facility in Colorado Springs Colorado
Colorado Springs, Colorado 80910
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Clinical Trial Facility in Cortlandt Manor New York
Cortlandt Manor, New York 10567
?
mi
from
Cortlandt Manor, NY
Click here to add this to my saved trials
Clinical Trial Facility in Dayton Ohio
Dayton, Ohio 45409
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Clinical Trial Facility in Daytona Beach Florida
Daytona Beach, Florida 32117
?
mi
from
Daytona Beach, FL
Click here to add this to my saved trials
Clinical Trial Facility in DeLand Florida
DeLand, Florida 32720
?
mi
from
DeLand, FL
Click here to add this to my saved trials
Clinical Trial Facility in Duncansville Pennsylvania
Duncansville, Pennsylvania 16635
?
mi
from
Duncansville, PA
Click here to add this to my saved trials
Clinical Trial Facility in Endwell New York
Endwell, New York
?
mi
from
Endwell, NY
Click here to add this to my saved trials
Clinical Trial Facility in Fargo North Dakota
Fargo, North Dakota 58122
?
mi
from
Fargo, ND
Click here to add this to my saved trials
Clinical Trial Facility in Great Falls Montana
Great Falls, Montana 59405
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
Clinical Trial Facility in Green Cove Springs Florida
Green Cove Springs, Florida
?
mi
from
Green Cove Springs, FL
Click here to add this to my saved trials
Clinical Trial Facility in Henderson Nevada
Henderson, Nevada
?
mi
from
Henderson, NV
Click here to add this to my saved trials
Clinical Trial Facility in Houston Texas
Houston, Texas
?
mi
from
Houston, TX
Click here to add this to my saved trials
Clinical Trial Facility in Indianapolis Indiana
Indianapolis, Indiana 46202
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Clinical Trial Facility in Inglewood California
Inglewood, California 90301
?
mi
from
Inglewood, CA
Click here to add this to my saved trials
Clinical Trial Facility in Iowa City Iowa
Iowa City, Iowa 52242
?
mi
from
Iowa City, IA
Click here to add this to my saved trials
Clinical Trial Facility in Jacksonville Florida
Jacksonville, Florida 32209
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Clinical Trial Facility in Las Vegas Nevada
Las Vegas, Nevada 89135
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Clinical Trial Facility in Little Rock Arkansas
Little Rock, Arkansas
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Clinical Trial Facility in Littleton Colorado
Littleton, Colorado 80120
?
mi
from
Littleton, CO
Click here to add this to my saved trials
Clinical Trial Facility in Louisville Kentucky
Louisville, Kentucky 40202
?
mi
from
Louisville, KY
Click here to add this to my saved trials
Clinical Trial Facility in Malvern Arkansas
Malvern, Arkansas 72104
?
mi
from
Malvern, AR
Click here to add this to my saved trials
Clinical Trial Facility in Marquette Michigan
Marquette, Michigan
?
mi
from
Marquette, MI
Click here to add this to my saved trials
Clinical Trial Facility in Miami Florida
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Clinical Trial Facility in Mission Viejo California
Mission Viejo, California 92691
?
mi
from
Mission Viejo, CA
Click here to add this to my saved trials
Clinical Trial Facility in Mount Pleasant South Carolina
Mount Pleasant, South Carolina 29464
?
mi
from
Mount Pleasant, SC
Click here to add this to my saved trials
Clinical Trial Facility in Munster Indiana
Munster, Indiana 46321
?
mi
from
Munster, IN
Click here to add this to my saved trials
Clinical Trial Facility in New York New York
New York, New York 10032
?
mi
from
New York, NY
Click here to add this to my saved trials
Clinical Trial Facility in Newport Beach California
Newport Beach, California 92660
?
mi
from
Newport Beach, CA
Click here to add this to my saved trials
Clinical Trial Facility in Norfolk Virginia
Norfolk, Virginia 23507
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
Clinical Trial Facility in Norman Oklahoma
Norman, Oklahoma 73069
?
mi
from
Norman, OK
Click here to add this to my saved trials
Clinical Trial Facility in Oklahoma City Oklahoma
Oklahoma City, Oklahoma
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Clinical Trial Facility in Pittsburgh Pennsylvania
Pittsburgh, Pennsylvania
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Clinical Trial Facility in Ponte Vedra Florida
Ponte Vedra, Florida 32081
?
mi
from
Ponte Vedra, FL
Click here to add this to my saved trials
Clinical Trial Facility in Port Charlotte Florida
Port Charlotte, Florida 33952
?
mi
from
Port Charlotte, FL
Click here to add this to my saved trials
Clinical Trial Facility in Portland Maine
Portland, Maine 04102
?
mi
from
Portland, ME
Click here to add this to my saved trials
Clinical Trial Facility in Raleigh North Carolina
Raleigh, North Carolina 27607
?
mi
from
Raleigh, NC
Click here to add this to my saved trials
Clinical Trial Facility in Rapid City South Dakota
Rapid City, South Dakota 57701
?
mi
from
Rapid City, SD
Click here to add this to my saved trials
Clinical Trial Facility in Renton Washington
Renton, Washington 98057
?
mi
from
Renton, WA
Click here to add this to my saved trials
Clinical Trial Facility in Richmond Virginia
Richmond, Virginia 23227
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Clinical Trial Facility in San Antonio Texas
San Antonio, Texas 78224
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Clinical Trial Facility in Sanford Florida
Sanford, Florida 32771
?
mi
from
Sanford, FL
Click here to add this to my saved trials
Clinical Trial Facility in Savannah Georgia
Savannah, Georgia 31406
?
mi
from
Savannah, GA
Click here to add this to my saved trials
Clinical Trial Facility in Seattle Washington
Seattle, Washington 98105
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Clinical Trial Facility in Tacoma Washington
Tacoma, Washington
?
mi
from
Tacoma, WA
Click here to add this to my saved trials
Clinical Trial Facility in Thousand Oaks California
Thousand Oaks, California 91360
?
mi
from
Thousand Oaks, CA
Click here to add this to my saved trials
Clinical Trial Facility in Tucson Arizona
Tucson, Arizona 85724
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
Clinical Trial Facility in Tupelo Mississippi
Tupelo, Mississippi 38801
?
mi
from
Tupelo, MS
Click here to add this to my saved trials
Clinical Trial Facility in Tustin California
Tustin, California 92780
?
mi
from
Tustin, CA
Click here to add this to my saved trials
Clinical Trial Facility in Williamsville New York
Williamsville, New York 14221
?
mi
from
Williamsville, NY
Click here to add this to my saved trials
Clinical Trial Facility in Winston-Salem North Carolina
Winston-Salem, North Carolina
?
mi
from
Winston-Salem, NC
Click here to add this to my saved trials
Clinical Trial Facility in York Pennsylvania
York, Pennsylvania 17405
?
mi
from
York, PA
Click here to add this to my saved trials