Efficacy of Gabapentin in Prevention of Tourniquet Pain and Hypertension
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 64 |
| Updated: | 3/16/2015 |
| Start Date: | January 2012 |
| End Date: | February 2015 |
| Contact: | Jaime Ortiz, MD |
| Email: | jaimeo@bcm.edu |
| Phone: | 713-873-950 |
Efficacy of Gabapentin in Prevention of Tourniquet Pain and Hypertension During Orif of Tibia Fracture Under General Anesthesia
The purpose of the study is to find out if taking a dose of gabapentin 600 mg by mouth (po)
before surgery will help prevent the development of tourniquet pain and hypertension while
the tourniquet is inflated during orif of tibia fracture.
before surgery will help prevent the development of tourniquet pain and hypertension while
the tourniquet is inflated during orif of tibia fracture.
Inclusion Criteria:
- Patient ages 18-64
- ASA physical status 1-3
- Schedule for orif tibia fracture with use of pneumatic tourniquet
Exclusion Criteria:
- Allergy to study medications
- polytrauma
- lower extremity crush injury
- chronic opioid use
- sickle cell disease or trait
- peripheral vascular disease
- poorly controlled hypertension
- history of DVT/PE
- morbid obesity (BMI > 35)
- patient or surgeon refusal
- patient inability to properly describe postoperative pain to investigators
We found this trial at
1
site
Ben Taub General Hospital Located in the heart of the Texas Medical Center, Ben Taub...
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