The Effects of Work Schedule and Sleep Patterns on Caregivers' Health

BACKGROUND. Sleep deficiency (not getting enough sleep) is widespread in American adults and
can lead to many harmful health outcomes such as a higher risk of obesity, heart disease,
and diabetes. Sleep deficiency can also harm cognitive performance, which refers to one's
awareness and thinking ability. Sleep deficiency and sleep-related health issues are of high
interest among those who have irregular and/or extended work schedules, because such
schedules can interfere with normal biological rhythms of sleepiness and wakefulness.

PURPOSE. This study will examine the health and cognitive effects of work schedule and sleep
patterns in caregivers (such as nurses, laboratory technicians, and non-clinical hospital
staff). The investigators hypothesize that the nontraditional, irregular, and extended work
hours common in these professions will have adverse health and cognitive effects. The
purposes of this protocol are to:

- Enroll caregivers into a one year cohort study on the relationships among work
schedule, sleep, diet, chronic disease, and cognitive performance. (A cohort study
follows a group of participants over time to see how different behaviors or risk
factors affect health.)

- Collect data from caregivers on work schedule, sleep, diet, chronic disease, and
cognitive performance.

- Give personalized information and feedback to caregivers about these health factors.

- Educate caregivers about healthy diet and exercise choices.

- Collect saliva from caregivers for future research on the role of genes in health.
(Specimen collection for genetic testing will be offered as a separate option for study
participants.) RECRUITMENT. This study will use the Let's Get Healthy! health research
and education program (OHSU IRB #3694) as a platform for recruitment and data
collection. Caregivers will be invited to participate in a Let's Get Healthy! event and
will be given information prior to the event about the cohort study. At the Let's Get
Healthy! event, caregivers will first consent to the anonymous research study (OHSU IRB
#3694), in which demographic and health screening data are linked to a random number.
Caregivers will then have the option to consent to a cohort study, in which data are no
longer anonymous but instead linked to participants' names and contact information.

PROCEDURES. This cohort study piggybacks on procedures already approved for the Let's Get
Healthy! program (OHSU IRB #3694). Let's Get Healthy! is a study in which participants
provide anonymous data at health fairs through any or all of the following manners: short
computer surveys on cancer awareness, risk factors, and family history (with immediate
feedback given on cancer risk and prevention); short computer surveys on diet and sleep
patterns (with immediate printed feedback given); health screening measurements (blood
pressure, height, weight, waist circumference, body mass index, body fat percentage); a
finger stick to assess sugar and fat levels in blood; and a mouthwash swish to provide a
saliva specimen.

However, this cohort study (OHSU IRB #7542) will make the following changes and additions:

- Personal health data, instead of being anonymous, will be linked to participants' names
and contact information (for follow-up data collection).

- Let's Get Healthy! events will include cognitive performance tests, a preventative-care
survey, and a work schedule survey.

- Participants will provide data not only at an initial Let's Get Healthy! event, but
also at a follow-up event and during the time period between events. Between events,
participants will do the surveys on work schedule, diet, and sleep, and they will
complete cognitive performance tests.

- There will be a separate consent process for participants to provide a fully
identifiable saliva specimen.

DATA ANALYSIS. Participants' health data will be fully identifiable at the time of data
collection but will be coded and stored in a physically separate location from the
identifiable information. The link between identifiable information and coded health
information will be stored on a password protected computer, and all identifiable
information will be deleted upon completion of data analyses. Data will be analyzed to
explore relationships among work schedule, sleep, diet, body composition, metabolic health,
chronic disease, and cognitive performance in caregivers. Genetic relationships with these
factors will be analyzed in those who provided a saliva specimen during entry visit data
collection.