Prevention of Post-operative Pneumonia (POPP)
| Status: | Terminated |
|---|---|
| Conditions: | Lung Cancer, Cancer, Cancer, Cancer, Pneumonia, Gastrointestinal |
| Therapuetic Areas: | Gastroenterology, Oncology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/10/2018 |
| Start Date: | September 22, 2011 |
| End Date: | December 13, 2015 |
Prevention of Postoperative Pneumonia (POPP Study): A Study to Evaluate the Use of a Prophylactic Clinical Strategy to Prevent Postoperative Pneumonia in Patients Undergoing Thoracic Surgery
Postoperative pneumonia is a major complication in patients undergoing thoracic surgery. It
leads to considerable morbidity and contributes to perioperative morbidity. There is evidence
in literature that supports the use of strategies for improved oral hygiene and specialized
endotracheal tubes in preventing ventilator associated pneumonia (VAP) in mechanically
ventilated patients. This study aims at utilizing a combination of these interventions in the
perioperative period in patients undergoing planned thoracic surgical procedures.
leads to considerable morbidity and contributes to perioperative morbidity. There is evidence
in literature that supports the use of strategies for improved oral hygiene and specialized
endotracheal tubes in preventing ventilator associated pneumonia (VAP) in mechanically
ventilated patients. This study aims at utilizing a combination of these interventions in the
perioperative period in patients undergoing planned thoracic surgical procedures.
Inclusion Criteria:
1. Patients with lung lesions undergoing anatomic resection
(lobectomy/segmentectomy/bilobectomy/pulmonary sleeve resection/pneumonectomy)
2. Patients with poor lung function (FEV1% <50% or DLCO<50% predicted or home oxygen
requirement) and lung lesions undergoing non-anatomic lung resection (i.e. wedge
resection).
3. Patients undergoing esophageal resection.
Exclusion Criteria:
1. Patients with ongoing symptomatic dental infections.
2. Patients with recent/ongoing pneumonia (<15 days from initial surgical patient
evaluation).
3. Patients who've received a therapeutic course of antibiotics within 15 days prior to
thoracic surgery.
4. Patients with a preexisting tracheostomy.
5. Age<18
6. Patients with an allergy to Peridex/chlorhexidine solution
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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