Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies
| Status: | Completed |
|---|---|
| Conditions: | Cancer, Blood Cancer, Anemia, Hematology |
| Therapuetic Areas: | Hematology, Oncology |
| Healthy: | No |
| Age Range: | 6 - Any |
| Updated: | 4/21/2016 |
| Start Date: | October 2011 |
| End Date: | December 2014 |
A Phase 2, Open-label Study of Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies
This is an open-label, multicenter, phase 2 clinical trial to evaluate the antitumor
activity of brentuximab vedotin as a single agent in patients with CD30-positive
nonlymphomatous malignancies.
activity of brentuximab vedotin as a single agent in patients with CD30-positive
nonlymphomatous malignancies.
Inclusion Criteria:
- Histologically-confirmed by central review CD30-positive nonlymphomatous malignancy
- Have failed, refused, or have been deemed ineligible for standard therapy
- Measurable disease
- Eastern Cooperative Oncology Group (ECOG) Performance Status score of 0 or 1 or a
Karnofsky or Lansky Performance Status score greater than or equal to 70
Exclusion Criteria:
- Primary diagnosis of lymphoma or central nervous system (CNS) malignancy
- History of another primary invasive malignancy that has not been definitively treated
or in remission for at least 3 years
- Evidence of active cerebral/meningeal disease
We found this trial at
29
sites
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
Fairfax, Virginia 22031
(703) 280-5390
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
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Oxnard, California 93030
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