Cost of Care for Juvenile Idiopathic Arthritis

SPECIFIC AIMS AND OBJECTIVES

The specific aims of this registry protocol are:

- To create and maintain a secure online database of patients with JIA

- To collect data elements related to cost of care in patients with JIA

- Compare standard outcome and disease activity measures to health care expenditures in
JIA

- To determine methods by which to reduce costs while improving outcomes and quality of
care

The study plans to enroll 300 or more subjects from 3 medical centers in the US over a 24
month period. Subjects in the study are patients with Juvenile Idiopathic Arthritis.

Enrollment into the protocol will include key demographic and clinical data including,
medication exposures, disease severity, and function including disease-specific data
elements; and estimates of health care service utilization and health care expenditures. Data
will be collected once per subject within the context of a standard of care visit.

Inclusion Criteria:

- Subject has been diagnosed with JIA by a pediatric rheumatologist according to
published criteria.

- Person providing consent must be able to read English.

- Subject (and/or parent/legal guardian) is able to provide informed consent and willing
to comply with study procedures.

Exclusion Criteria:

- Subject/ legal guardian is unwilling to provide consent, cannot read English, or does
not meet published criteria for JIA.

- Coexisting rheumatologic disorder

- Diagnosis of fibromyalgia

- Participation in a drug trial in the past 6 months.